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Endodermal Sinus Tumor in Children.

Journal of the Korean Pediatric Society 1988;31(6):772-778.
Published online June 30, 1988.
Endodermal Sinus Tumor in Children.
Jae Sun Jung1, Hyo Seop Ahn2, Chang Yee Hong2
1Department of Pediatrics, Seoul City Youngdungpo Hospital, Seoul, Korea
2Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
소아의 내배엽동종양 -33례에 대한 임상적 고찰-
정재선1, 안효섭2, 홍창의2
1서울특별시립영등포병원 소아과
2서울대학교 의과대 학 소아과학교실
Received: 30 November 1987   • Accepted: 5 January 1988
Thirty-three cases of endodermal sinus tumor were reviewed. They were diagnosed at Seoul National University Hospital over the last 9 years. Sixteen were testicular, 12 were sacrococcygeal and the others were mediastinal, vaginal, ovarian, retrovesical and tongue endodermal sinus tumor. Endodermal sinus tumor of the tongue was the first reported case in the world. Serum 公-fetoprotein of 32 cases was elevated at diagnosis and well correlated with clinical course. In testicular endodermal sinus tumor 9 were treated by inguinal orchiectomy: 3 were relapse free for more than 2 years, but 2 cases were relapsed. The other 7 cases were treated by inguinal orchiectomy and cheomtherapy with or without radiotherapy: 3 of them were relapse free for more than 2 years after completion of chemotherapy but 2 were relapsed. Further study with larger series is required to evaluate the optimal treatment of testicular endodermal sinus tumor.
Key Words: Endodermal sinus tumor, Yolk sac tumor

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