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A Case of Thrombotic Thrombocytopenic Purpura in Childhood.

Journal of the Korean Pediatric Society 1988;31(4):511-518.
Published online April 30, 1988.
A Case of Thrombotic Thrombocytopenic Purpura in Childhood.
Dong Kun Hyun, Jung Bae Lee, Chang Hyun Yang, Kir Young Kim
Department of Pediatrics, Yonsei University, College of Medicine, Seoul, Korea
소아에서 관찰된 혈전성 혈소판 감소성 자반증 1례
현동근, 이정배, 양창현, 김길영
연세대학교 의과대학 소아과학교실
Received: 5 September 1987   • Accepted: 20 November 1987
Abstract
Thrombotic thrombocytopenic purpura is clinically characterized by microangiopathic hemolytic anemia, thrombocytopenia, fever, renal disorder and transient bizarre neurological symptoms. Its essential histological lesion consists of numerous complete or, more often, incomplete occlusions of the arterioles and capillaries by hyaline material. We have experienced a case of thrombotic thrombocytopenic purpura in infancy. The patient was a one year and 4 month-old who complains petechiae on the whole body since birth and generalized tonic convulsion with eyeball deviation 20 days before admission. She showed microangiopathic hemolytic anemia, thrombocytopenia on laboratory findings and cerebral infarction on right frontoparietal area on brain C-T scan. We diagnosed her thrombotic thrombocytopenic purpura and presented a brief review of literature.
Key Words: Thrombotic Thrombocytopenic Purpura


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