| Clinical Study of the role of Exchange Transfusion for Treatment in Neonatal DIC. |
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Myung Shik Lee, Jin Sung Lee, Chul Lee, Dong Gwan Han |
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Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea |
| 신생아 DIC치료에 있어서 교환수혈의 효과에 대한 임상적 고찰
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이명식, 이진성, 이 철, 한동관 |
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연세대학교 의과대학 소아과학교실 |
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| Abstract |
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This study was made of 9 cases of neonatal septicemia complicated with DIC and sclerema,
who were admitted to the pediatric department of YUMC from January 1981 to June 1983.
The following results were obtained;
1) A higher incidence was observed in males(77.8%), low birth weight(66.7%) and1 pretnature(77.8%).
2) The mean onset of sepsis was noticsd on 4.4 days of life. The most common presenting symptoms and signs were poor Moro reflex, poor feeding lethargy and jaundice.
3) More than 3 abnormal laboratory findings were shown in all neonates in the DIC study including platelet count, PT, PTT, Fibrinogen and FDP. Positive blood cultures were found in 7 cases and the 2 cases with negative blood culture resulting in DIC were suspected to result from asphyxia and hypothermia.
4) Associated diseases were DIC, sepsis, asphyxia, sclerema, meningitis and RDS etc.
5) Survival rate was 44.4%. Considering the above results, exchange transfusion may be effective as supportive therapy in neonatal septicemia complicated with DIC and sclerema which did not responded to antibiotic treatment.
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| Key Words:
Exchang transfusion, NeonatalJDIC, Neonatal septicemia.
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