A Clinical Study of Viral Hepatitis in Childhood.

Lee, Ju Kyeong; Kim, Chan Yong

Original Article

Journal of the Korean Pediatric Society 1984;27(11):1078-1087.
Published online November 30, 1984.

A Clinical Study of Viral Hepatitis in Childhood.

¹Department of Pediatrics，Busan Mary knoll Hospital
²Department of Pediatrics, College of Medicine，Busan National University

소아 바이러스성 간염의 임상적 관찰

이주경^¹^, 김찬영^¹

^¹부산메리놀병원 소아과
^²부산대학교 의과대학 소아과학교실

Abstract

A clinical study has been made on 158 children with viral hepatitis who had been admitted to the pediatric department of Busan Maryknoll Hospital during a 472 year period from January 1979 to June 1983. The following results were obtained. 1) Viral hepatitis was 1.61% of all the pediatric inpatients. Positive rate of HBsAg was 25.9% of viral hepatitis. 2) Age incidence showed even distribution after 5 years of age in the HBsAg positive group and after 2 years of age in the HBsAg negative group. Ratio of male to female patients was 1.7 : 1. There was no significant seasonal difference between the two groups. 3) On admission, fever, abdominal pain, neusea, vomiting and sclera jaundice were significantly more common in the HBsAg negative group. 4) On admission, the mean serum total bilirubin level was 6.5±5.8mg% in the HBsAg positive group and 4.3±4. Omg% in the HBsAg negative group. There was a significant difference between the two groups (p<0.01). 5) On admission, the mean ESR level was 10.5±5.7niin/hr in the HBsAg positive group and 13.2±6.8mm/hr in the HBsAg negative group. There was a significant difference between the two groups (p<0.05). 6) On admission, the mean TTT level was 4.1±2.9unit in the HBsAg positive group and 6.8土3.9unit in the HBsAg negative group. There was a significant difference between the two groups (p<0.01). 7) It was noted more frequently in the HBsAg negative group that serum total bilirabin, SGOT and SGPT returned to normal within 2 weeks of illness. 8) Among 17 HBsAg positive cases followed in OPD, HBsAg was found to become negative in 8 cases (47.0%) within 4 weeks and in 11 cases (64.7%) within 8 weeks of admission.

Key Words: Viral hepatitis, HBsAg.