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Clinical Study of Hand, Foot, and Mouth Disease and Herpangina.

Journal of the Korean Pediatric Society 1983;26(1):14-25.
Published online January 31, 1983.
Clinical Study of Hand, Foot, and Mouth Disease and Herpangina.
Tae Hoon Lee, Jae Ock Park, Chang Hwi Kim, Dong Whan Lee, Sang Man Shin, Sang Jhoo Lee
Department of Pediatrics, Soon Chun Hyang College、School of Medicine, Korea
Hand, Foot, and Mouth Disease (手• 足• 口病) 와 Herpangina 의 臨床的 觀察
李泰棄, 朴在玉, 金彭釋, 李東換, 申相滿, 李尙柱
順天鄕大學 醫學部 小兒科學敎室
A total of 211 children fullfilling all characteristics of Hand, Foot, and Mouth disease (H.F.,& M. Dis.) and 94 children of Herpangina were studied prospectively during epidemic period of 5 months, April through August, 1981 in Seoul, Korea. Maculopapular rash and vesicles that were changed in patterns from time to time were distributed on hands(97%), feet(95%), buttocks(46%), legs(45), arms(16%), trunk (3%), & face (1.4%) and vesicular ulcerative lesions were found on palate, uvular, anterior pillars (61%), tongue(45%), buccal mucosa(43%), gums(6%) and lips(0.9%) in H., F” & M. Dis. The most common symptoms were anorexia(72%) and fever(47%) in H., F., & M. Dis., whereas fever(89%) and anorexia(80%) were common to Herpangina. Rashes were lasted 2〜6 days in H., F., & M. Dis. Males were more affected than females in H., F., & M. Dis.(1.3 : 1) and Herpangina(1.5 : 1). H., F., & M. Dis. were occurred mostly under 4 years of age(93%) and Herpangina mostly under 2 years of age(82%). Enanthems were found in 79% of cases in H., F., & M. Dis. and 100% of Herpangina. Exanthems of H., F.» & M. Dis. were found in 100% of the patients, and in only 4% of the cases of Herpangina. The temperature ranged between normal and 39.2°C in H., F., & M.Dis. and between normal and 40.8°C in Herpangina. The fever lasted for 1 to 5 days in H.,F., & M. Dis., whereas 2 to 7 days in Herpangina. In younger children, exanthem has been seen on the buttocks, legs and arms frequently more than in older children with H., F., & M. Dis.In Herpangina, Larger sized enanthem, higher fever with longer duration were prevalent in. the younger age group.
Key Words: Hand, Foot, and Mouth Disease, Herpangina, Enanthem, Exanthem

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