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Hemagglutination and Drug Resistance of Escherichia coli Isolated from Children.

Journal of the Korean Pediatric Society 1980;23(9):687-694.
Published online September 15, 1980.
Hemagglutination and Drug Resistance of Escherichia coli Isolated from Children.
Sung Bae Park1, Sun Taik Rhim1, Kyu Cha Kim1, Tai You Ha2
1Department of pediatrics, Jeonbug National University Medical School, Korea.
2Department of Microbiology, Jeonbug National University Medical School, Korea.
小兒에서 分離한 大腸菌의 赤血球凝集 및 藥劑 耐性
朴成培1, 林順澤1, 金圭次1, 河大有2
1全北大學校 醫科大學 小兒科學敎室
2全北大學校 醫科大學 微生物學敎室
Abstract
A hemagglutination(HA)-typing system has been developed for the presumptive identification of enterotoxigenic Escherichia coli(ETEC) possessing the colonization factor antigens(CFA) Seventy-seven E. coli strains from pediatric patients with or without diarrhea were examined for the mannose-resistant(MR) HA or mannose-sensitive(MS) HA of human, bovine, chicken, and guinea pig erythrocytes and their antibiotic resestances. A significant proportion(68%) of the isolates exhibited the HA pattern of NNNN(experssed in the order human/bovin/chicken/guinea pig erythrocytes), and 10% of the isolates exhibited NNSS, known as the pattern about half of enteropathogenic E. coli serogroups produced. Sixty-nine strains(88%) were resistant to one or more antibiotics; 55(80%) were reristant to four or more antibiotics. The strains showed multiple drug resistance were more higher in HA-positive strains(92% of HA-positive strains) than in HA-negative strains(76% of HA-negative strains) and all of the HA-positive strains with human erythrocytes were resistant to 4 or more antibiotics. There were no significant differences between HA patterns and antibiotic resistance in both the strains from the patients with or without diarrhea. In summary, although the causative organisms in cases of diarrhea of this study have not been established, the date herein suggested that ETEC possessing CFA which produce RRRN or NRRN HA pattern was not participated in this diarrhea.


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