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A Case of leukemic Reticuloendotheliosis: A case report and literature review.

Journal of the Korean Pediatric Society 1979;22(11):996-1002.
Published online November 15, 1979.
A Case of leukemic Reticuloendotheliosis: A case report and literature review.
Se Ho Chang1, Sun Ja Lee1, Jong Hoon Park1, Dong Hyuk Kum1, Jung Dal Lee2
1Department of pediatrics, Korea General Hospital, Seoul, Korea.
2Department of Pathology, Korea General Hospital, Seoul, Korea.
白血病性 網內增殖症 1 例
張世昊1, 李善子1, 朴宗薰1, 琴東爀1, 李重達2
1高麗病院 小兒科
2高麗病院 病理科
Leukemic reticuloendotheliosis (L.R.E.) was first described as a clinical and pathological entity by Ewald in 1923. LRE is a rare neoplastic disease of the hematopoietic system that is characterized cliniclly by chronic course with an insidious onset. marked splenomegaly with absence of substantial lymphadenopathy and predominant in male and characterized histologically by the presence of circulating abnormal mononuclear cells with many cytoplasmic projections, which have been refered to ??airy cells frequently. Splenectomy appeared to be the most beneficial treatment at present for those patients with massive splenomegaly and hypersplenism and chemotherapy is of little benefit in the treatment in LRE. Recently, the authors had the opportunity to observe a two year and eight old male child at this hospital whose clinical course and pathologid features were consistent with LRE. Splenectomy is performed and discharged with relatively good conditions.

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