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Two Cases of Methemoglobinemia due to Ingestion of 4,4'-Diaminodiphenylsulfone (Dapsone, DDS)

Journal of the Korean Pediatric Society 1975;18(8):594-597.
Published online August 31, 1975.
Two Cases of Methemoglobinemia due to Ingestion of 4,4'-Diaminodiphenylsulfone (Dapsone, DDS)
Whi Dai Kim, Chang Hwi Kim, Sang Man Shin, Joong Sik Kim
Department of Pediatrics, College of Medicine, Kyung Hee University Seoul, Korea
4, 4" -Diaminodiphenylsulfone(Dapsone, DDS) 로 因한 Methemoglobinemia 의 2例
金喜大, 金彭釋, 申相滿, 金仲植
慶照大學校 醫科大學 小兒科學敎室
Abstract
Two cases of methemoglobinemia due to accidental ingestion of DDS was reported. On physical examination, cardiac or pulmonic diseases couldn’t be detected, but cyanosis was remarkable on their lips, cheeks, fingers, and oral mucosa. Methemoglobin was determined, the results of which were 25%, and 30. 4% of total hemoglobin respectively. Review of literature was made briefly.


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