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Common variable immunodeficiency, as defined by World Health Organization classification of
primary immunodeficiency, is a heterogenous group of disorders with hypogammaglobulinemia,
decreased ability to produced antibody following antigenic challenge, and increased incidence of
infections. The disorder was often familial, but no mode of inheritance has been discerned. Clinical
fingings are recurrent bacterial infections, particularly respiratory infection.
Laboratory evaluations in common variable immunodeficiency demonstrate decrease in... |