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Clinical Lecture
Treatment of Symptoms Related to Common Cold in Children
Ki Young Lee
Clin Exp Pediatr. 1999;42(4):449-461.   Published online April 15, 1999
Original Article
A Nationwide Clinical Study of Acute Respiratory Distress Syndrome in Children
Soo Jung Choi, Do Suck Jeong, Jae Won Oh, Ha Baik Lee, Im Ju Kang, Kwang Woo Kim, Kyu Earn Kim, Ki Bok Kim, Young Ho Rah, Kang Seo Park, Byong Kwan Son, Ki Young Lee, Sang Il Lee, Ji Tai Choung, Young Mi Hong
Clin Exp Pediatr. 1999;42(1):23-31.   Published online January 15, 1999
Purpose : Acute respiratory distress syndrome(ARDS) is the final course of acute lung injury. It results from various etiological origins and pathophysiologic mechanisms, and has a mortality rate of approximately 60-70%. Although the confirmative incidence of ARDS in children is yet unknown, the increasing incidence of ARDS has been reported in Korea. In the present study, we report ARDS diagnosed...
Thymopentin Therapy in Atopic Dermatitis
Geun Woong Noh, Ki Young Lee
Clin Exp Pediatr. 1998;41(9):1268-1272.   Published online September 15, 1998
Purpose : Atopic dermatitis is a chronic relapsing inflammatory skin disease that results from allergic reaction. Steroid therapy has become a major therapeutic modality for treatment of atopic dermatitis. Several immunomodulatory therapies have been tried for atopic dermatitis. In this study thymopentin therapy was performed and its clinical effects and laboratory results were evaluated. Methods : Atopic dermatitis with typical clinical...
Decrease of Plasma Th2 Cytokines by Interferon(IFN) -γ Therapy in Atopic Dermatitis
Geun Woong Noh, Woo Gill Lee, Dong Hee Cho, Ki Young Lee
Clin Exp Pediatr. 1998;41(8):1128-1134.   Published online August 15, 1998
Purpose : Atopic dermatitis is characterized by reduced IFN-γ production and increased IL-4 production. As a result, IgE production increases in atopic dermatitis. In the previous studies, it was reported that recombinant IFN-γ therapy is effective in treatment of severe atopic dermatitis. In this study, changes of plasma IFN-γ, IL-4, IL-5 and IL-10 concentration by IFN-γ therapy were studied in...
House Dust Mites Sensitivity in Korean Atopic children; Correlation between Skin Reaction and Relative Concentration of Specific IgE by ELISA
Ji Hong Kim, Soo Young Lee, Byeung Ju Jeung, Kye Earn Kim, Dong Soo Kim, Ki Young Lee
Clin Exp Pediatr. 1994;37(12):1701-1708.   Published online December 15, 1994
House dust mites, Dermatophagoides farinae and Dermatophagoides pteronyssius, have been identified as the main sources of house dust allergen and are considersed the most important causative allergen in the etiology of allergic respiaratory disease and allergic rhinitis. To evaluate the incidence of positive skin reactivity to house dust mites and relationship between total serum IgE levels and specific IgE antibody to...
Case Report
One Case of Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome due to Mycoplasma pneumoniae In fection
Soo Kyung Lee, Joon Soo Lee, Soo Young Lee, Byung Ju Jeoung, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1993;36(10):1441-1446.   Published online October 15, 1993
Bronchiolitis obliterans is an infrequent disorder characterized by partial or complete obstruction of bronchi and bronchioles by fibrous tissue following an insult to the lower respiratory tract. In the pediatric population, Bronchiolitis obliterans has most frequently been preceded by respiratory tract infection by adenovirus, influenza, measles. But it may occur in young adults after mycoplasma infection. We experienced the case...
Five Cases of Thymic Hyperplasia
Soo Kyoung Lee, Soo Young Lee, Kyu Eun Kim, Byung Ju Chung, Ki Young Lee
Clin Exp Pediatr. 1992;35(10):1435-1442.   Published online October 15, 1992
Diagnosis of thymic hyperplasia may be quite difficult because thymus has not always sail appearance and it sometimes appears to be a huge mass in the mediastinum. This fact causes sometimes diagnostic thoracotomy or often make primary physicians fail in treatment and transfer their patients to other hospitals. But in most cases diagnosis can be made by a lateral chest...
2 Cases with Adult Respiratory Distress Syndrome in Infant and Young Child
Hye Jung Joo, Im Jae Park, Joon Soo Lee, Soo Young Lee, Byeung Ju Jeoung, Kyu Earn Kim, Ki Young Lee, Hyunee Yim, Soon Won Hong, Woo Hee Jung
Clin Exp Pediatr. 1992;35(8):1118-1126.   Published online August 15, 1992
Adult respiratory distress syndrome has been described as a clinical syndrome of respiratory distress and need for mechanical ventilation with positive end-expiratory pressure, diffuse pulmonary infiltration on thoracic roentgenogram, impaired pulmonary compliance, decreased lung volumes and capacities, increased alveoloarterial oxygen gradient and hyaline membrane formation. It is the clinical manifestation of injury to the terminal alveolocapillary unit as a result...
A Case of Endobronchial Tuberculosis Accompanied with Obstructive Emphysema
Myung Goo Min, Seong Chul Shin, Byeung Ju Jeong, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1992;35(8):1113-1117.   Published online August 15, 1992
We experienced a case of endobronchial tuberculosis accompanied with obstructive emphsema which appears just before total atelectasis, in a 4/12 year old male who was admitted to the department of pediatrics, Yonsei university College of Medicine. On chest X-ray, left side total emphysema was found and on bronchogram, punched out defect was noted at the site of the left main...
Original Article
A Case of Right Lung Agenesis Associated with Right Hemifacial Atrophy.
Jung Tak Kim, Young Mi Chung, Dong Goo Lee, Byeong Ju Jeoung, Kyu Earn Kim, Ki Young Lee, Jin Suk Suh
Clin Exp Pediatr. 1990;33(12):1723-1728.   Published online December 31, 1990
Unilateral lung agenesis is a rare disease with associated anomalies of soft tissue, the musculos- keletal system, cardiovascular system and gastrointestinal system in 50-60% of cases. When associat- ed anomalies are absent, the disease may not be discovered during a lifetime, but in most of the cases, frequent respiratory infection or associated anomalies make it possible for diagnosis of the disease. Since early diagnosis...
A Study on the Growth Pattern, History of Respiratory Illness and Family History in Acute Bronchiolitis.
Dong Won Choi, Byung Ju Jung, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1990;33(5):623-631.   Published online May 31, 1990
The authors evaluated the growth pattern, history of frequent respiratory illness and family history in 111 infants who were admitted to the Department of Pediatrics, Yonsei University Hospital with the diagnosis of acute bronchiolitis from Sept. 1986 to Jun. 1988. The results of the study were as follows: 1) The sex incidence of bronchiolitis was higher in males compared with the sex incidence of the total...
A case of Endobronchial Tuberculosis Accompanied by Embedded Lymph Node.
Kyoung Hoon Choi, Jeong A Hwang, Byeung Ju Jeong, Kyu Earn Kim, Ki Young Lee, Fan Chen Mong, Hee Dae Park
Clin Exp Pediatr. 1990;33(3):386-392.   Published online March 31, 1990
We experienced a case of endobronchial tuberculosis accompanied by an embedded lymph node in a 1 3/12-year old male who was admitted to the Department of Pediatrics, Yonsei University College of Medicine. On bronchogram, a punched out defect was noted at the site of the right main bronchus from where the right upper lobe bronchus and right intermediate bronchus branched. Although bronchoscopy was performed three...
A Case of Congenital Esophageal Duplication Cyst.
Kyoung Hoon Choi, Chung Ah Whang, Byung Ju Jeaung, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1990;33(1):111-116.   Published online January 31, 1990
A case of congenital esophageal duplication cyst has been studied in a 10-month old male Korean infant. He had suffered from cough, fever and dyspnea since 4 months of age, and he had been admitted 4 times to other hospitals before he visited severance hospital due to aggravated cough and dyspnea. An esophagogram and computed tomogram of chest were done and a post-tracheal mass...
Clinical Studies on Bronchiectasis in Children.
Hye Sook Lee, Byeung Ju Jeong, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1989;32(12):1669-1677.   Published online December 31, 1989
Clinical data and findings of 22 cases of bronchiectasis in children which were confirmed by bronchogram and treated at Yonsei University Hospital during the period of January 1980 to January 1987 were riewed. The results were briefly summarized as follows; 1) Bronchiectasis was seen most frequently within the age group of 6〜 10 year (54.5%) and 72.7% of all patients were under 10 years of age. 2) Identifiable...
Two Cases of Chronic Bronchitis in Children Who Showed Perfusion Defects at the Base of Lung.
Hyeon Soo Lee, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(12):1663-1668.   Published online December 31, 1988
We experienced two cases of chronic bronchitis in 9 4/12 year female & 10 year old male who were admitted at department of Pediatrics, College of Medicine, Yonsei University. In which all laboratory findings including chest X-ray were normal, but on the scitiscan perfusion defects were noted at the base of lung and clinically improved accociated with disappearance of perfusion defects ossurred after treatment. The...
2 Cases of Congenital Bronchial Anomalies Associated with Recurrent Pneumonia in Children.
Choong Sun Kang, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(12):1657-1662.   Published online December 31, 1988
We have experienced 2 cases of congenital bronchial anomalies in children. In one case, the right middle lobe bronchus originated from the right upper lobe bronchus, and all branches of the bronchial tree including the right main bronchus showed severe deformity. In another case, two upper lobe bronchi originated from the right main bronchus. These bronchial anomalies were associated with chronic and recurrent respiratory...
Two Cases of Allergic Rhinitis in Children Diagnosed by Youlten's Peak Nasal Inspiratory Flow (PNIF) Meter.
Yil Sub Lee, In Suck Ryu, Kyu Eun Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(11):1527-1532.   Published online November 30, 1988
Two asthmatic children associated with allergic rhinitis were performed nasal provocation test with various allergens which were detected by allergic skin test. The degree of nasal obstruction induced by allergens were measured with Youlten’s Peak Nasal Inspiratory Flow (PNIF) meter and Red top,Trichophyton and Sagebrush were known as causative allergens in case 1, and Chrysanthemum was detected as causative allergen in case 2. The...
Non-specific Immunotherapy with Histamine-Gammalobulin Preparations in Chronic Respiratory Group Patients and Non-atopic Asthmatic Children.
Byeung Ju Jeoung, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(10):1308-1314.   Published online October 31, 1988
We evaluated the therapeutic effect of non-specific immunotherapy with Histamine- gammahlobulin in 60 patients. Among them 22 patients were chronic respiratory group patients who were under 2 years of age and suffered from frequent respiratory tract infections, and 38 patients were as follows: 1) Excluding the patients who received 9 weeks therapy for the test period, the mean duration of Histamine-gammaglobulin therapy in the chronic respiratory...
Diagnostic Value of Perfusion Lung Scan on Airway Foreign Body in Children.
Ki Young Lee, Kyu Earn Kim
Clin Exp Pediatr. 1988;31(6):715-722.   Published online June 30, 1988
The authors evaluated diagnostic value of perfusion scan of the lung in the children who had foreign bodies. Perfusion lung scan with 99mTc MAA was performed in 23 cases of children with foreign bodies in the airway. The results of study were as follows; 1) The majority of 23 cases with foreign body in airway was infants and young children, and 19 cases (82.6%) of them was...
A Case of Pulmonary Paragonimiasis Whose Parenchymal Lesions Dtected by Tomogram and Perfusion Scan of the Lung.
Jung Keun KIm, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(4):519-525.   Published online April 30, 1988
Recently, we experienced a case of pulmonary paragonimiasis in a 8 year old boy with a chief complaint of intractable pleural fluid for one year. The cystic cavity was detected by tomogram, but not by chest X-ray and apparant regional pulmonary perfusion defect was also detected at the same site of that lesion by lung scan. We report this case with brief review of...
A Study on Predicted Values of Peak Expiratory Flow Rate in Primary School Children.
Soon Wook Lim, Ki Young Lee
Clin Exp Pediatr. 1986;29(10):1104-1113.   Published online October 31, 1986
Wright’s peak flow meter, which was desigend as a simple and reliable device for measuring the peak expiratory flow rate(PEFR) is now used worldwide as a measurement of ventilatory capacity. PEFR is an especially useful parameter in the management of childhood asthma and other obstructive pulmonary diseases. It has been used in inhalation bronchial challenge tests to identify offending allergens such...
Case Report
A case of Unilateral Absence of Pulmonary Artery.
Kwang Sin Joh, Dong Soo Kim, Chul Joo Ryu, Shin Heh Kang, Sung Kyu Lee, Ki Young Lee, Dong Shik Chin
Clin Exp Pediatr. 1986;29(5):559-563.   Published online May 31, 1986
Unilateral Absence of Pulmonary Artery(UAPA) is a rare disease. It is characterized by no specfiic cardiopulmonary symptoms in general. We experienced a case of UAPA in a 9 year-old female patient with the chief complaint of abnormal chest Xray finding. Lung perfusion scan, cardiac catheterization with pulmonary and aortic angiography confirmed the diagnosis of right side UAPA.
Original Article
A Measurement of Measles Antibodies among the Age Between 6 to 15 Months
Ki Young Lee, Sang Woo Kim, Kyoung Tae Hwang, Kyu Chong Choi, Jong Soo Kim, Chang Ju Cho, Baek Keun Lim, Hyun Sook Kim, Dong Soo Kim
Clin Exp Pediatr. 1986;29(4):375-380.   Published online April 30, 1986
To determine the proper age of the measles vaccination, we must know the time when the passively transferred measles antibody from mother disappeared. Because it can be a major factor for vaccine failure to take the measles vaccine to the children who still have the passive immunity. We measured the degree of immunity of 50 children with the age between...
A Study on Methacholine Challenge Test in Asthmatic Children.
Yong Gab Kwon, Ki Young Lee
Clin Exp Pediatr. 1985;28(11):1073-1081.   Published online November 30, 1985
A diagnosis of asthma is most confidently made by actually exposing the patient to the suspected allergen (by either inhalation or ingestion) and evoking the allergic response. Several methods are known for these kinds of provocation test for the diagnosis and differential diagnosis of asthma and one of the widely-used such test is methacholine challenge test which utilized the fact...
A Study of Measurement of Physical Development and Cardiothoracic Ratio in the Asthmatic Children.
Hee Dae Park, Ki Young Lee
Clin Exp Pediatr. 1985;28(8):756-765.   Published online August 31, 1985
Pediatric asthma is characterized by high incidence and symptoms of severe respiratory difficulty and causes great suffering by the patients due to the chronicity and the recurrent nature of the disorder. In addition, growth and development of the child are hindered and creates problems in both the psychological and education aspects of life. Changes in the lung capacity in asthmatic...
Case Report
The Two Cases of Children with Buckwheat Allergy Confirmed by Oral Challenge Test.
Yong Baik Kwon, Ki Young Lee
Clin Exp Pediatr. 1985;28(6):604-609.   Published online June 30, 1985
The authors experienced two cases of buckwheat allergy. The first case was a 10-7/12 year old male boy and second case a 5-1/12 year old male boy. The chief complaints were cough, dyspnea, rhinorrhea and nasal obstruction for about 7 and 3 years, respectively in both cases. The diagnosis of these cases was confirmed by oral challenge tets. We report...
Original Article
Bacterial Isolation by Bronchial Washing.
Hee Jung Chun, Ki Young Lee
Clin Exp Pediatr. 1984;27(8):753-759.   Published online August 31, 1984
Bronchial washings and throat cultures have been performed on 41 cases of chronic or recurrent respiratory infection who were admitted to the department of Pediatrics, Yonsei University from July 1981 to December 1983. The results are as follows; 1)By bronchial washing, organisms were isolated in 74.1% of the all pneumonia patients and 57.1% of the pulmonary tuberculosis with complication patients,...
A Study on oral Spanich Provocation Test.
Yu Young Chang, Ki Young Lee
Clin Exp Pediatr. 1983;26(11):1055-1062.   Published online November 30, 1983
In asthmatic children, there were many cases who showed positive reactions to food allergens in allergy skin test. But food itself is not usually the cause of asthma, differing from inhalant allergen. Spinach was the third most common positive skin test with 47.8 percent following house dust and house dust mite in our studies of 205 asthmatics who had visited the allergy clinic...
Case Report
A case of Bronchial Asthma Improved by Chlorpramazine Administrayion.
Bok Lyun Park, Chang Joo Cho, Ki Young Lee
Clin Exp Pediatr. 1982;25(11):1159-1163.   Published online November 30, 1982
Asthma is a disease of multicausal etiology. But psychologic factors were assumed one of the important factors. We present a case of bronchial asthma aggravated to emotional upset and subsided by chlorpromazine administration. 11 years old female patient was admitted 4 times due to asthmatic attack which was. developed after psychologic upset On laboratory studies, IgE, total eosinophile count and pulmonary function tests were within...
Recovery of Bilateral Renal Vein Thrombosis after Peritoneal Dialyis in a Newborn Neonate.
Young Mo Sohn, Nan Ae Kim, Sang Hak Park, Ki Young Lee, Pyung Kil Kim
Clin Exp Pediatr. 1981;24(8):772-776.   Published online August 15, 1981
A 4 day old male neonate with severe dehydration, uremia, and hyperbilirubinemia presented with bilateral renal vein thrombosis. Following exchange transfusion and peritoneal dialysis renal function returned to normal without nephrectomy. The importance of adequate and prompt management of renal failure to expect the spontaneous recanalization is stressed. Because of the high mortality rate associated with the nephrectomy in neonates,...