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Allergy

Food allergies and food-induced anaphylaxis: role of cofactors

Meeyong shin

Clin Exp Pediatr. 2021;64(8):393-399. Published online November 12, 2020

Web of Science 10 Crossref 24

Question: What are the roles of cofactors in food allergies and food-induced anaphylaxis?
Finding: Cofactors reportedly play a role in approximately 14%–30% of anaphylactic reactions. Cofactors such as exercise, infection, nonsteroidal anti-inflammatory drugs, dehydration, and alcohol can increase intestinal permeability and antigen uptake, thereby causing allergic symptoms.
Meaning: Routine assessment of the possible involvement of cofactors is essential for the management of patients with food-induced anaphylaxis.

DOI: https://doi.org/10.3345/cep.2020.01088

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