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Original Article
High degree of supervision improves adherence to inhaled corticosteroids in children with asthma
Geun Mi Park, Hye Won Han, Hee Se Kim, Jae Youn Kim, Eun Lee, Hyun-Ju Cho, Song-I Yang, Young-Ho Jung, Soo-Jong Hong, Hyung Young Kim, Ju-Hee Seo, Jinho Yu
Clin Exp Pediatr. 2015;58(12):472-477.   Published online December 22, 2015
Purpose

Adherence to treatment with inhaled corticosteroids (ICS) is a critical determinant of asthma control. The objective of this study was to assess factors that determine adherence to ICS therapy in children with asthma.

Methods

Fifty-eight children with asthma, aged 5 to 16 years, used ICS with or without a spacer for 3 months. Adherence rates as measured from questionnaires and canisters, asthma...

Fractional exhaled nitric oxide and forced expiratory flow between 25% and 75% of vital capacity in children with controlled asthma
Ji-Yong Yoon, Sung-Il Woo, Heon Kim, Yong-Han Sun, Youn-Soo Hahn
Clin Exp Pediatr. 2012;55(9):330-336.   Published online September 14, 2012
Purpose

Fractional exhaled nitric oxide (FeNO) and forced expiratory flow between 25% and 75% of vital capacity (FEF25-75) are not included in routine monitoring of asthma control. We observed changes in FeNO level and FEF25-75 after FeNO-based treatment with inhaled corticosteroid (ICS) in children with controlled asthma (CA).

Methods

We recruited 148 children with asthma (age, 8 to 16 years) who had maintained...

The role of inhaled and/or nasal corticosteroids on the bronchodilator response
Ju Kyung Lee, Dong In Suh, Young Yull Koh
Clin Exp Pediatr. 2010;53(11):951-956.   Published online November 30, 2010
Purpose

To compare the profiles of the bronchodilator response (BDR) among children with asthma and/or allergic rhinitis (AR) and to determine whether BDR in these children is reduced by treatment with inhaled and/or nasal corticosteroid.

Methods

Sixty-eight children with asthma (mean age, 10.9 years), 45 children with comorbid asthma and AR (mean age, 10.5 years), and 44 children with AR alone (mean age,...

Effects of inhaled corticosteroids on bone mineral density and bone metabolism in children with asthma
Ic Sun Choi, Jung Hye Byeon, Seung Min Lee, Kyong Suk La, Yeon Joung Oh, Young Yoo, Kee Hyoung Lee, Ji Tae Choung
Clin Exp Pediatr. 2009;52(7):811-817.   Published online July 15, 2009
Purpose : Inhaled corticosteroids (ICS) are used as first-line agents for the treatment of persistent asthma; however, their use is accompanied by apprehension of potential systemic adverse effects. This study aimed to assess the effects of ICS on bone mineral density (BMD) and bone metabolism in children with asthma. Methods : From February 2008 to September 2008, 26 asthmatic children treated...