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Review Article

The treatment of pediatric chronic myelogenous leukemia in the imatinib era

Jae Wook Lee, Nack Gyun Chung

Clin Exp Pediatr. 2011;54(3):111-116. Published online March 31, 2011

Childhood chronic myelogenous leukemia (CML) is a rare hematologic disease, with limited literature on the methods of treatment. Previously, allogeneic hematopoietic stem cell transplantation (HSCT) was considered the only curative treatment for this disease. Treatment with imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase (TKI), has resulted in prolonged molecular response with limited drug toxicity. Imatinib is now implemented...

DOI: https://doi.org/10.3345/kjp.2011.54.3.111

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