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Clinical Observation on Newborn using Artificial Ventilator

Journal of the Korean Pediatric Society 1992;35(3):322-329.
Published online March 15, 1992.
Clinical Observation on Newborn using Artificial Ventilator
Hyun Seung Park, Myung Ik Lee, Soon Wha Kim, Don Hee Ahn
Department of pediatrics, National Medical Center, Seoul, Korea
인공호흡기를 사용한 신생아에 대한 임상적 고찰
박현승, 이명익, 김순화, 안돈희
국립의료원 소아과
Abstract
Retrospective clinical analysis of 5 and a half yeas experience with artificial ventilaion on 187 neonas in NICU of National Medical Center, from Jan. 1985 to Dec. 1990, was done. The results were as follows; 1) Number of patients, who required respiratory therapy with aritificial ventilation, was 187 and the percentage of these patients to all hospitalized neonates was 11.4%. 2) Number of male patients was 107(57.2%) and of femal was 80 (42.8%), and male to female ratio was 1.3:1. 3) Major neonatal conditions requird the artifical ventilation were prematurity incluidng apnea of prematurity (70.1%), hyaline membrane disease 59.9%, meconium aspiration syndrome 13.4%, perinatal asphyxia 10.2%, pneumonial 4.3% and others. 4) Major high risk factors were prematurity, institutional baby, acidosis, cesarean section delivery, very-low-birth-weight infant, low Apgar score and meconium-staind infant in the order of frequency. 5) Complications were air-leak syndrome including pneumothoras 12.3%, sepsis 8.6%, intracranial hemorrhage 8.6%, intracranial hemorrhage 8.6%, gastrointestinal or pulmonary hemorrhage 4.8%, bronchopulmonary dysplasia 1.6% and visual field defect ith some evidnce of retinopathy of prematurity 1.1%/ 6) The incidence of case, which needed intensive respiratory therapy including endotracheal intubation within 24 hours of age, was esarean sectin delivery 78.8%, prematurity 44.6% and full-term infant 50%. The case of cesarean delivery needed artificial ventilation earlier than the case of vaginal delivery. 7) Overall mortality was38.9%. The mortality of the inant of gestational age below 3 weeks was 58.5%, that of gestational age between 37 week and 42 weeks was 37.5% and that of postmaturity was 55.6%. 8) The bateria cultured at the tip of endotracheal tube was gram-negative organism in 66 cases and gram-positive organism in 28 cases. 9) Among expired cases, early mortality rate within 7 days was 61.8%. Eighty ive point three percent died within 4 weeks and only 14.7% died after 4 weeks.
Key Words: Artificial ventilation, Newborn


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