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2 Cases with Adult Respiratory Distress Syndrome in Infant and Young Child

Journal of the Korean Pediatric Society 1992;35(8):1118-1126.
Published online August 15, 1992.
2 Cases with Adult Respiratory Distress Syndrome in Infant and Young Child
Hye Jung Joo1, Im Jae Park1, Joon Soo Lee1, Soo Young Lee1, Byeung Ju Jeoung1, Kyu Earn Kim1, Ki Young Lee1, Hyunee Yim2, Soon Won Hong2, Woo Hee Jung2
1Department of Pediatrics, Yonsei University, College of Medicine, Seoul, Korea
2Department of Pathology, Yonsei University, College of Medicine, Seoul, Korea
범발성 폐렴을 동반한 영유아기 성인형 호흡곤란 증후군 2례
주혜정1, 박임재1, 이준수1, 이수영1, 정병주1, 김규언1, 이기영1, 임현이2, 홍순원2, 정우회2
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 병리학교실
Adult respiratory distress syndrome has been described as a clinical syndrome of respiratory distress and need for mechanical ventilation with positive end-expiratory pressure, diffuse pulmonary infiltration on thoracic roentgenogram, impaired pulmonary compliance, decreased lung volumes and capacities, increased alveoloarterial oxygen gradient and hyaline membrane formation. It is the clinical manifestation of injury to the terminal alveolocapillary unit as a result of a variety of direct and indirect pulmonary insults. In spite of mechanical ventilation and intensive care, when the progressive pulmonary infiltration and prologed hypoxemia have been observed, physicians should be aware of the potential for ARDS to develop. We have experienced two cases with ARDS in a 7/12 year-old boy and a 12/12 year-old boy who were admitted to our department of Pediartrics, because of dyspnea and fever. They received mechanical ventilation with PEEP and intensive care, but the pulmonary infiltration and hypoxemia were prolonged and then expired at 13th and 7th hospital day respectively, due to respiratory acidosis and hypoxemia. In these two cases, autopsy findings were compatible with ARDS. A brief review of literatures was made.
Key Words: Adult respiratory distress syndrome, Infancy, Peak inspiratory pressure, Positive endexpiratory pressure

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