| A Clinical Study of Primay Gastrointestinal Lymphoma in Childhood |
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Hye Jung Joo1, Chuhl-Joo Lyu1, Byung Soo Kim1, Euy Ho Hwang2, Chang Ok Suh3, Woo Ick Yang4, Woo Hee Chung4 |
1Department of Pediatrics, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea
2Department of General Surgency, College of Medicine, Yonsei University, Seoul, Korea
3Department of Radiation Oncology, College of Medicine, Yonsei University, Seoul, Korea
4Department of Pathology, College of Medicine, Yonsei University, Seoul, Korea |
| 소아 원발성 위장관 림프종에 대한 임상적 고찰 |
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주혜정1, 유철주1, 김병수1, 황의호2, 서창옥3, 양우익4, 정우희4 |
1연세대학교 의과대학 소아과학교실, 연세암센터
2연세대학교 의과대학 외과학교실
3연세대학교 의과대학 치료방사선과학교실
4연세대학교 의과대학 병리학교실 |
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| Abstract |
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The 18 cases of primary gastrointestinal lymphoma patients admitted to the Department of Pediatrics and Yonsei Cancer Center, College of Medicine, Yonsei University, during 15 years from January, 1975 to December, 1989 were reviewed on the bases of clinical characteristics, treatment, and survival rates.
The results were summarized as follows;
1) The age of patients ranged from 3 years to 14 years, and the man age was 7.6±3.5 years. The sex ratio of male to female was 26.:1.
2) The primary sites of lymphoma were ileum in 10 cases(55%), cecum in 4 cases(22%), stomach in 2 cases(11%), jejunum and duodenum in 1 case(6%), respectively.
3) The most common initial presenting symptom was abdominal paint(61%), abdominal mass(50%), nausea and vomiting(39%), abdominal distension(17%), anemia(11%), diarrhea(6%), weight loss(6%), and fever (6%)in order.
4) The histological subtypes by Rappaport classification in 18 cases revealed that diffuse pooly differentiated lymphocytic type was the commonest(39%), and diffuse histiocytic type(33%), diffuse mixed lymphocytic & histiocytic type(17%), and undifferentiated Burkitt type(11%)was followed in descending order.
5) Retrospective staging classification by Murphy showed 8 cases to have presented as Stage Ⅱ(44%), 7 cases as Stage Ⅲ(39%), and 3 cases as Stage Ⅳ(17%), Overall 5 year survival rate was 44% in all patients with primary gastrointestinal lymphoma, 75%, in Stage Ⅱ, 29% in Stage Ⅲ. The 3 patients with Stage Ⅳ were expired within the 5 months after initial diagnosis
6) The results of this study would indicate that the important factors in primary gastrointestinal lymphoma seems to be the stage of disease at the time of diagnosis and surgical resectability. |
| Key Words:
Primary Gastrointestinal Lymphoma, Childhood |
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