| Effect of Cultured Thymic Epithelium Transplantation in a Patients with Severe Combined Immunodeficiency |
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Soo Kyung Yun, Byoung Ho Cha, Woo Seung Jeoun, Dong Soo Kim |
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Department of Pediatrics, Yonsei University, College of Medicine, Seoul, Korea |
| 중증 복합 면역부전증 환아에서의 Cultured Thymic Epithelium Transplantation |
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윤수경, 차병호, 전우성, 김동수 |
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연세대학교 의과대학 소아과학교실 |
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| Abstract |
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Severe combined immunodeficiency disease is caused by a group of genetic disease characterized by abnormal function of T and B lymphocytes.
The treatment of choice for severe combined immunodeficiency disease is a HLA mached bone marrow transplant, but transplantation of cultured thymus epithelium was used to treat severe combined immunodeficiency disease in case of that mached, related bone marrow donors were not available.
We are reporting a case with severe combined immunodeficiency disease who was treated by transplantation of cultured thymic epithelium, which showed temporary increase of peripheral lymphocytes and improvement of clinical pictures. |
| Key Words:
Chltured thymic epitelium transplantation, Severe combined immunodeficiency disease |
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