Gastrofiberscopic Findings and Helicobacter pylori Gastritis in Children with Recurrent Abdominal Pain |
Jeong Kee Seo1, Je Geun Chi2, Eui Chong Kim3 |
1Department of Pediatrics, Seoul National Universty College of Medicine, Seoul, Korea 2Department of Pathology, Seoul National Universty College of Medicine, Seoul, Korea 3Department of Clinical Pathology, Seoul National Universty College of Medicine, Seoul, Korea |
반복성 복통증 환아에서의 내시경 소견 및 H. Pylori 위염 |
서정기1, 지제근2, 김의종3 |
1서울대학교 의과대학 소아과학교실 2서울대학교 의과대학 병리학교실 3서울대학교 의과대학 임상병리학교실 |
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Abstract |
Gastrofiberscopic findings and the presence of Helicobacter pylori (H. pylori) were studied prospectively in children with recurrent abdominal pain (RAP). Endoscopic findings in 707 children with RAP revealed that 243 children (34.3%) showed abnormal findings including gastritis in 16.9%, duodenitis in 10.4%, esophagitis in 5.7%, duodenal ulcer in 5.7%, and gastric ulcer in 1.1% of children with RAP.
Endoscopic biopsy of the antrum showed chronic active gatritis in 25.2%, chronic gastritis in 64.7%, and no abnormalities in 10.1% of children with RAP.
H. pylori was investigated by urease test, Giemsa stain and culture method with endoscopic biopsy specimens in 159 children with RAP; 27% of them showed H. pylori gastritis.
In 82.5% of children with chronic active gastritis, H. pylori was postitive. Forty three percent of the H. pylori gastritis showed multiple micronodules in the antrum. Wheather H. pylori causes or is coincidentally associated with RAP are unknown. Further active endoscopic investigations in children with RAP are needed to elucidate the role of the endoscopic and histologic abnormalities, or the presence of H. pylori on the pathogenesis of RAP. |
Key Words:
Recurrent abdominal pain, Gastrofiberscopy, Helicobacter pylori, Children |
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