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Clinical Study on Infants of Diabetic Mothers

Journal of the Korean Pediatric Society 1993;36(3):347-355.
Published online March 15, 1993.
Clinical Study on Infants of Diabetic Mothers
Eun Eui Kim, Min Jeong Kim, Yang Sook Choi, Son Sang Seo
Department of Pediatrics, Il Sin Christain Hospital, Pusan, Korea
당뇨병 산모에서 출생한 신생아에 대한 임상적 고찰
김은의, 김민정, 최양숙, 서손상
일신 기독병원 소아과
Abstract
A clinical observation was performed on the 80 cases of neonates born from diabetic mothers among the total of 34,936 neonates delivered at Il Sin Christian Hospital from January 1985 to December 1989. The results were as follows : 1) The incidence of infants of diabetic mothers was 0.23%, among whom gestational diabetic mothers were 63 cases(78.7%) and overt diabetic mothers were 17 cases(21.63%). 2) Among the complications of pregnancy and delivery, preeclampsia was most frequent as 33.8%, following by urinary tract infection (13.8%), polyhydramnios(1.3%), diabetic ketoacidosis(1.3%). 3) According to the gestational age, prematurity was 11.3%, full term 78.7% and post term 10%. And according to the growth state, small for date infants were 11.3%, appropriate for date infants 53.7% and Large for date infants 35%. 4) The incidence of giant babies(over 4,000gm) was 30.0% and sex ratio of male to female was 1.1:1 in infants of diabetic mothers. 5) The most frequent clinical manifestation was tachypnea(45.3%), following by poor feeding(20.0%), cyanosis(18.7%). 6) According to the laboratory findings, 53.7% showed hypoglycemia, 36.3% hyperbilirubinemia, 25 hypocalcemia, 15% polyc;ythemia. 7) On the chest X-ray, there were pulmonary infiltraton and hyaline membrane disease in 3.2% each other and pulmonary congestion and wet lung in 1.6% each other. 8) The incidence of congenital anomaly was 13.8% in 80 cases of infants of diabetic mothers, and congenital heart disease was most frequent as 3 cases.
Key Words: Infants of diabetic mothers


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