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A Clinical Study on Patients with Porencephaly

Journal of the Korean Pediatric Society 1993;36(7):975-981.
Published online July 15, 1993.
A Clinical Study on Patients with Porencephaly
Sung Yoon Cho, Jai Yoon Kim, Kwang Sun Han, Sa Jun Chung, Chang Il Ahn
Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea
소아 공뇌증(Porencephaly)의 임상적 고찰
조성윤, 김재윤, 한광선, 정사준, 안창일
경희대학교 의과대학 소아과학교실
Porencephaly is relatively rare condition defined by a defect or cavity in the cerebrum owing to a developmental malformation or to a destructive lesion. Forty-five porencephaly patients diagnosed by Brain CT were clinically analyzed and the following results were obtained. 1) By the age group presenting initial symptoms, the peak incidence was from 1 month to below 3 years old. 2) In initial symptoms, seizure, spastic weakness, headache were showed in order of frequency. But 7 cases (15.5%) were asymptomatic. 3) The latency of diagnosis after presenting initial symptoms was various from the symptom onset time to 10 years. 4) The subsequent symptoms were as follows: spastic weakness, speech disturbance, gait disturbance, mental retardation, sensory loss and seiqure showed independently or combined. 5) As etiologic factor, 21 cases (46.7%) were congenital, 16 cases (35.5%) were post-traumatic or post-operative and 8 cases (17.8%) were perinatal. 6) The prognosis was seen various from mild to severe. Out of 45 cases , 29 cases (64.4%) were no complications. But the prognosis in patients with post-traumatic or postoperative etiological factors was poor. With the advent of brain CT and the resultant capability of detecting structural defect and cerebral lesions responsible for epilepsy or focal neurolocic signs, porencephaly was seen to be readily recongizable by CT examination. Since porencephaly is a significant contributor to the spectrum of CNS lesion and benign condition, its recognition is important in determining prognosis and therapy.
Key Words: Porencephaly, Brain CT

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