Plasma Norepinephrine Levels in Infants and Children with Congestive Heart Failure |
Sang Woog Lee, Myung Sung Kim, Sang Lak Lee, Tae Chan Kwon, Chin Moo Kang |
Department of Pediatrics, Keimyung University, School of Medicine, Taegu, Korea |
소아 울혈성 심부전증 환자의 혈장 Norepinephrine치의 변동 |
이상욱, 김명성, 이상락, 권태찬, 강진무 |
계명대학교 의과대학 소아과학교실 |
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Abstract |
To characterize the sympathetic nervous system response to congestive heart failure in infants and children, plasma norepinephrine levels were measured in 29 patients aged 4 months to 15 years undergoing routine cardiac catheterization at Dong San Hospital, Keimyung University during the period of 4 months from November 1990 to February 1991.
Plasma norepinephrine levels were significantly higher in patients with heart disease and congestive heart failure than in those without congestive heart failure (p<0.001).
A significant association was found between the level of plasma norepinephrine and severity of the symptoms of congestive heart failure.
Plasma norepinephrine levels correlated well with size of the shunt (Qp/Qs) (γ=0.75), degree of pulmonary arterial pressure(γ=0.79) and degree of right ventricular pressure(γ=0.82). |
Key Words:
Norepinephrine, Congestive heart failure |
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