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The Clinical Observation in Kawasaki Disease

Journal of the Korean Pediatric Society 1994;37(2):167-174.
Published online February 15, 1994.
The Clinical Observation in Kawasaki Disease
Min-Young Park, Gye-Sik Shim, Sung-Ho Cha, Chang-Il Ahn
Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea
Kawasaki병의 임상적 고찰
박민영, 심계식, 차성호, 안창일
경희대학교 의과대학 소아과학교실
Abstract
One-hundred ninty five cases with Kawasaki disease who diagnosed and treated at the Department of Pediatrics, Kyung Hee University Hospital from January 1985 to June 1993, were investigated for their clinical manifestations and laboratory findings, and cardiac complications. The results are as follows: 1) Most patients (92.8%) were under 5 years of the age. 2) Boys were more prevalent than girls, as a ratio of 2.3:1 3) The incidence of principal symptoms and sign were fever over 5 days (89.8%), bilateral conjunctival injection (78.5%), changes of oral mucosa and lip (82.3%), skin eruption (72.8), changes in extremities (58.5%), and cervical lymphadenopathy (47.2%). 4) The main laboratory findings observed were anemia (29.2%), leukocytosis (90.8%), thrombocytosis (89.7%), increased ESR (85.1%), positive CRP (100%), increased sGOT (33.3%), increased sGPT (34.9%), pyuria (41.5%), proteinuria (5.6%), microscopic hematuria (9.7%), and abnormalities of EKG(23.5%). 5) Abnormal findings of the heart were found in 27.2% by echocardiogram and coronary aneurysm and dilatation were present in 19.7%. 6) Among 147 cases assessed by echocardiogram, the abnormalities of coronary artery were present in 16 of 92 cases (17.4%) in the aspirin and intravenous gammaglobulin treated group, as compared with 13 of 55 cases (23.6%) in the aspirin treated group.
Key Words: Kawasaki disease, Clinical observation


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