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Pheochromocytoma in Children

Journal of the Korean Pediatric Society 1994;37(7):961-968.
Published online July 15, 1994.
Pheochromocytoma in Children
Tae Sue Ha1, Jae Hong Park2, Il Soo Ha3, Hae Il Cheong3, Yong Choi3, Hyung Ro Moon3, Gui Won Park4
1Now in Department of Pediatrics, Chungbuk National University College of Medicine, Cheongju, Korea
2Now in Department of Pediatrics, Busan National University College of Medicine, Busan, Korea
3Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
4Department of Pediatric Surgery, Seoul National University College of Medicine, Seoul, Korea
소아 갈색세포종의 임상적 고찰
하태선1, 박재홍2, 하일수3, 정해일3, 최용3, 문형로3, 박귀원4
1서울대학교 의과대학 소아과학교실
2서울대학교 의과대학 소아과학교실
3서울대학교 의과대학 소아과학교실
4서울대학교 의과대학 소아외과학교실
Abstract
We Reviewed 10 hypertensive children with pheochromocytoma retrospectively and the following results were obtained. 1) Out of 10 patients, 7 were male and 3 female. Age ranged from 5.5 years to 13.8 years and their median age was 9.9 years. 2) They complained of sweating, lethargy, headache, or chest pain and so on, Hypertension were noticed in all patients. Heart murmurs were detected in 7 patients and hypertensive retinopathy in 70% 3) The three cases arised at extraadrenal gland and bilaterality was seen in 3 patients. In the view of diagnosis, abdominal sonography, computerized tomography and urine VMA test revealed the sensitivity of 100%.But MIBG scan showed 60% in sensitivity. 4) Waiting for operation, their hypertension were controlled by adrenergic blockers or calcium channel blockers. They received tumorectomy successfully except one who was in hypertensive state after operation and followed up through OPD. In conclusion, high suspicion for the existence of phechromocytoma from the clinical manifestations should be entertained in any pediatric patients and biochemical and imaging studies were mandatory. Furthermore, for the accurate localization of tumors, several imaging studies should be collaborated.
Key Words: Pheochromocytoma, Children


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