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A Clinical Study of Childhood Systemic Lupus Erythematosus

Journal of the Korean Pediatric Society 1994;37(9):1235-1244.
Published online September 15, 1994.
A Clinical Study of Childhood Systemic Lupus Erythematosus
Young-Jun Kim, Young Don Kim, Jae Hong Park, Su Young Kim, Hee-Ju Park
Department of Pediatrics, College of Medicine, Pusan National University, Pusan, Korea
소아 전신성 홍반성 낭창의 임상적 고찰
김영준, 김영돈, 박재홍, 김수영, 박희주
부산대학교 의과대학 소아과학교실
Abstract
To Evaluate the clinical characteristics of childhood-onset systemic lupus erythemoatosus (SLE) and analyse the factors related to outcome of renal function in lupus nephritis, we reviewed medical records of 18 cases of SLE diagnosed at the Department of Pediatrics, Pusan Nationsl University Hospital from January 1981 to December 1990. The results were as was 1:2.6 1)Male to female ratio was 1:2.6. 2)Nephropathy was the most common initial impression, and 8 cases were diagnosed as SLE at first. 3)The clinical menifestation was ANA(+), malar rash, renal disorder, hematologic disorder in frequency. 4)Diffuse proliferative lupus nephritis was the most common in renal histopathologic studies. 5)Among the follow-up cases, active lupus was 39%, remission was 28%. 6)As factors related to outcome of lupus nephrits were, hypertension and proteinuria were siginificant statistically.
Key Words: Systemic Lupus Erythematosus


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