| Two Cases of Familial β-Thalassemia Minor |
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Jeong Hwa Hwang1, Hyeon Jeong Lee1, Jun Hur1, Gae Soon Yeo1, Hee Jin Kim1, Chan Yung Kim1, Tae Jun Yun2 |
1Department of Pediatrics, Choon-Hae Hospital, Pusan, Korea
2Department of Clinical Pathology, Choon-Hae Hospital, Pusan, Korea |
| 모녀에서 발생한 β-Thalassemia Minor 2례 |
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황정화1, 이현정1, 허준1, 여계순1, 김희진1, 김찬영1, 윤태준2 |
1춘해병원 소아과
2춘해병원 임상병리과 |
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| Abstract |
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The β-thalassemia minor is a hereditary microcytic, hypochromic anemia characterized by decerased producion of β-globin polypeptide chain. The β-thalassemia minor should be clinically differentiated from iron deficiency anemia.
The thalassemia are common in the Medeterranean region, the Middle Ease, the Africa, Indea, and Thailand, but rare in Korea.
The authors experienced two cases of familial β-thalassemia minor 4-year 7-month-old female patient and her mother. The peripheral blood smear and hemoglobin electrophoresis of the patient and her mother revealed the findings of decreased MCV(57.8fl, 65.3gl), MCH(17.1pg, 19.7pg), microcytic hypochromic erythrocytes, poikilocytosis, anisocytosis, and elevated percentage of Hb A2 fraction (5.9%, 7.0%)
A brief review of related literatures was added. |
| Key Words:
β-Thalassemia minor |
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