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Pulmonary Function Test in Korean Neonates by Expiratory Flow-Volume Curve

Journal of the Korean Pediatric Society 1996;39(1):53-62.
Published online January 15, 1996.
Pulmonary Function Test in Korean Neonates by Expiratory Flow-Volume Curve
So Young Park, Kyung Hyo Kim, Gyoung Hee Kim
Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, Korea
정상 신생아에서 호기 유량-기량 곡선의 폐기능 측정치에 대한 연구
박소영, 김경효, 김경희
이화여자대학교 의과대학 소아과학교실
: Neonatal pulmonary function test(PFT) adds a new dimension to the understanding and care of the infant at risk for lung dysfunction. PFT can be identified the risk for pulmonary problems and safely and effectively diagnosed, quantified, and qualified the dysfunction. So it is possible to early institution of prophylatic respiratory therapy in such neonates and it can improved the dysfunction or reduce the incidence of both acute a and chronic complications. The purpose of this present study was to get the normal values of pulmonary function test in normal neonates
: We evaluated 332 normal neonates at Ewha Womans University Hospital from Feb. 1994 to Oct. 1994. We performed PFT by tidal breathing flow-volume loop and non-invasive passive expiratory flow-volume technique.
: 1) The mean respiratory rate was 51.0¡¾12.0/min and tidal volume 7.4¡¾2.9 ml/kg. 2) In the tidal breathing pattern, %V․PTEF was 0.42¡¾0.17, PTEF/TV 2.36¡¾0.76, TEF25/ PTEF 0.80¡¾0.10 and ME/MI 0.89¡¾0.25, and the shape of loop was oval. 3) The mean respiratory system compliance by passive expiratory flow-volume technique in normal neonates was 1.52¡¾0.93ml/cmH2O/kg and resistance 0.052¡¾0.039 cmH2O/ml/sec. 4) The values of PFT were not different according to sex or postnatal age(p>0.05).
: The measured values of pulmonary function test in normal neonates could be used in the future as reference values of pulmonary function in neonates with variable respiratory diseases, and could be aid in understanding the respiratory physiology and pathology of neonates through companing the measured values of pulmonary function by other method.
Key Words: Neonate, Pulmonary function test, Expiratory flow-volume curve

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