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A Case of Nonfamilial Generalized Gastrointestinal Juvenile Polyposis with Pancytopenia

Journal of the Korean Pediatric Society 1996;39(3):423-430.
Published online March 15, 1996.
A Case of Nonfamilial Generalized Gastrointestinal Juvenile Polyposis with Pancytopenia
Jong Ook Kim1, Heung Pyo Kong1, Kang Seo Park1, Wan Seob Kim1, Chun Hee Lee2
1Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea
2Department of Clinical Pathology Presbyterian Medical Center, Chonju, Korea
범혈구 감소증이 동반된 범 위장관 연소성 용종증 1례
김종욱1, 공흥표1, 박강서1, 김완섭1, 이춘희2
1전주예수병원 소아과
2전주예수병원 임상병리과
Abstract
In contrast to the child with a solitary juvenile polyp, generalized gastrointestinal juvenile polyposis have a much different clinical course. In generalized juvenile polyposis blood loss can be considerable and iron-deficiency anemia is a common observation. Although it is usually regarded as a benign condition, juvenile polyposis may predispose to cancer of the gastrointestinal tract. We experienced a case of nonfamilial generalized gastrointestinal juvenile polyposis with pancytopenia in a 15 year-old male patient who had hospitalized because of intermittent rectal bleeding with anemia for three years. Histological examination of polyps from affected patient revealed a spectrum of change from juvenile polyps, to juvenile polyps with adenomatous changes. Subtotal colectomy, rectal mucosectomy, and endorectal pull-through procedure were successfully performed. No complication has occured since the discharge. A brief review of related literatures is also presented.
Key Words: Juvenile polyposis, GI tract, Pancytopenia


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