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A Case of Juvenile Granulosa Cell Tumor of the Ovary

Journal of the Korean Pediatric Society 1997;40(2):279-283.
Published online February 15, 1997.
A Case of Juvenile Granulosa Cell Tumor of the Ovary
Jong Ook Kim, Heung Pyo Kong, Wan Seob Kim, Myoung Jin Ju
Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea
유년형 난소 과립막세포종 1례
김종욱, 공흥표, 김완섭, 주명진
전주예수병원 소아과
Juvenile granulosa cell tumor(JGCT) is one of the sex cord stromal tumors of the ovary ocurring in the first two decades of life. These tumors are different from adult granulosa cell tumor(AJCT) with regard to clinical and pathological fetures. Follicles are often irregular, Call-exner bodies are rare, and luteinization is frequent. The tumor may besolid, cystic, orboth. The most common presenting symptoms are abnormal uterine bleeding and pain. Breast swelling, pain and tenderness may also be associated with unopposed estrogen secretion by granulosa celltumors. The tumor should be removed as soon as the diagnosis is estabilished. The juvenile granulosa cell tumor has a good overall prognosis because fewer than 5% of these tumors in children are malignant.
Key Words: Juvenile granulosa celltumor, Ovary

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