| The Retrospective Study on Antibiotics Treatment in Acute Gastroenteritis |
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Ji Hye Kim, Sung Hee Oh |
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Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea |
| 비세균성 급성 위장관염의 치료에서 항생제 사용의 타당성에 대한 평가 |
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김지혜, 오성희 |
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한양대학교 의과대학 소아과학교실 |
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| Abstract |
Purpose
: Most of the gastroenteritis due to viruses and some bacteria can be successfully
managed by oral and/or intravenous fluid-electrolyte replacement and antibiotic therapy is
unnecessary and even harmful. It is, however, not uncommon practice to prescribe antibiotics when
acute gastroentritis is suspected. Therefore authors analysed the clinical courses of the patients
treated for acute non-bacterial gastroenteritis in a university hospital to assess the propriety of
antibiotic usage in the treatment of acute non-bacterial gastroenteritis.
Methods
: Ninty six patients hospitalized at Hanyang University Hospital from September 1993 to
February 1995 due to acute non-bacterial gastroenteritis were included in this retrospective study.
Fifty six patients received antibiotics (Group I) and the rest 40 patients did not (Group II). Clinical
symptoms including dehydration, diarrhea, vomiting, temperature, and other clinical courses were
analysed and compared between the two groups.
Results
:
1) Average age of the patients is 1.76¡¾0.24 years old and not significantly different between the
two groups.
2) The number of patients with moderate or severe dehydration on admission were greater in
Group II compared to Group I.
3) Frequency and duration of diarrhea prior to hospitalization were not different between the two
groups. However, more number of patients in Group I compared to Group II suffered from
aggravation of diarrhea during hospitalization.
4) Frequency and duration of vomiting were not different between the two groups.
5) Duration of temperature elevation prior to hospitaliztion was not different between the two
groups: however during the hospitalization, duration and height of temperature elevation were
significantly longer and greater in Group I compared to Group II.
6) Duration of hospitalization, the time from hospitalization to recovery, and duration of
intravascular cannulation were significantly longer in Group I compared to Group II.
7) Occurrence of complication was not different between the two groups and rash and paralytic
ileus are the ones frequently observed.
Conclusion
: The study results illustrates that antimicrobial administration appears not to be
beneficial, but rather have harmful effect on the course of acute non-bacterial gastroenteritis.
Therefore the overuse of antibiotics on patients with acute nonbacterial gastroenteritis should be
restraint. |
| Key Words:
Acute gastroenteritis, Antibiotics |
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