| A Clinical and Histological Study of Allergic Colitis in Infant |
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Jae Bok Kim1, Kyung Mo Kim1, Ki Soo Kim1, Soo Young Pi1, Yang Soon Park2 |
1Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
2Department of Diagnostic Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea |
| 영아 알레르기성 대장염의 임상 및 병리학적 고찰 |
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김재복1, 김경모1, 김기수1, 피수영1, 박양순2 |
1울산대학교 의과대학 소아과학교실
2울산대학교 의과대학 진단병리학교실 |
Correspondence:
Kyung Mo Kim, Email: 1
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| Abstract |
Purpose
: This study was done to evaluate the clinical and pathologic aspects of allergic colitis.
Methods
: This study evaluated 19 infants who presented with fresh blood mixed stools. Limited
colonoscopy and biopsy were performed. Among the 19 infants, 13 infants were diagnosed as
allergic colitis by histological findings. We analyzed the clinical and histological characteristics of
13 infants.
Results
: Male and female were 8 and 5 respectively. The mean age of the infants was 3 months(4
days to 12 months). Major symptoms were rectal bleeding(13), mucoid stool(6), diarrhea(5),
vomiting(2). Feedings before diagnosis were breast milk(3), formula milk(4), formula and breast
milk(5), and weaning diet(1). In labortory data, anemia(2) and eosinophilia(12) were found in some
infants. Endoscopic findings were focal erythema(7), nodularity(1), erythema and nodularity(4),
hemorrhage(1). Histopathologic finding was eosinophilic infiltration in lamina propria with preserved
mucosal architecture in all. In addition, cryptitis(13), lymphoid follicular hyperplasia(7), crypt
abscess(1) were also observed. All the infants improved with cessation of rectal bleeding and
diarrhea within three days after dietary change.
Conclusion
: Allergic colitis should be considered as one of the major cause of rectal bleeding in
healthy appearing infants. Limited colonoscopy and biopsy should be considered in establishing a
definitive diagnosis. |
| Key Words:
Allergic colitis, Eosinophilic colitis, Infant, Rectal bleeding, Colonoscopy |
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