Fatal Doudenal Ulcer Bleeding in Status Asthmaticus Treated with Theophylline and Steroids |
Sang Woo Lee, Chang Keun Kim, Churl Young Chung, Young Doug Kim |
Department of Pediatrics, College of Medicine, Inje University Sanggye Paik Hospital, Korea |
Theophylline과 Steroid로 치료받은 천식환아의 Theophylline과 Steroid로 치료받은 천식환아의 |
이상우, 김창근, 정철영, 김영덕 |
인제대학교 의과대학 상계백병원 소아과학교실 |
Correspondence:
Sang Woo Lee, Email: 1 |
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Abstract |
It is generally agreed that theophylline preparations and steroids should be given intravenously for
status asthmaticus. Theophylline can potentially have adverse gastrointestinal effects including
abdominal pain, nausea, vomiting, and hematemesis. Upper gastrointestinal bleeding in patients
treated with corticosteroids without a past history of upper gastrointestinal bleeding has been
reported rarely. But the etiologic significance of the stress of status asthmaticus, administration of
theophylline or corticosteroids in the development of ulcer has been open to question. We report a
case of 8-year-old boy with status asthmaticus treated with these medications and later found to
have a bleeding duodenal ulcer for which emergency surgery was necessary. |
Key Words:
Theophylline, Steroids, Status asthmaticus, Bleeding duodenal ulcer |
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