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A Case of Chorea in the Recovery Phase of Pneumococcal Meningitis

Journal of the Korean Pediatric Society 1998;41(5):719-723.
Published online May 15, 1998.
A Case of Chorea in the Recovery Phase of Pneumococcal Meningitis
Eun Ah Suh1, Dong Un Kim1, Yoon Kyung Lee1, Bung Jun Choi1, Young In Kim2, Ik Jun Lee1
1Department of Pediatrics, Catholic University, Medical College, Seoul, Korea
2Department of Neurology, Catholic University, Medical College, Seoul, Korea
폐렴구균성 뇌막염의 회복기에 발생한 무도증 1례
서은아1, 김동언1, 이윤경1, 최병준1, 김영인2, 이익준1
1가톨릭대학교 의과대학 소아과학교실
2가톨릭대학교 의과대학 소아과학교실
Correspondence: 
Eun Ah Suh, Email: 1
Abstract
Movement disorders(chorea, athetosis, ballism) are a rare complication that develops during the course of bacterial meningitis although associations with tuberculous meningitis are established to some extent. Movement disorders are generally believed to reflect injury to the basal ganglia, thalamus, cerebellum and cerebral cortex. Ischemic infarctions of these areas have been proposed as the cause of dyskinesias in bacterial meningitis. We experienced a case of chorea which developed in the recovery phase of pnemococcal meningitis in a 37-month-old boy. The choreic movement was initially misinterpreted as a seizure, and anticonvulsants were administered. The movement continued during the alert state in spite of anticonvulsant therapy but subsided during sleep. EEG showed severely depressed background activitiy with no epileptiform discharge. When the movement was recognized as a choreic movement, anticonvulsants were withheld and haloperidol was administered orally. The abnormal movement gradually disappeared in 3 months. But like the two other previously reported cases of postmenigitic movement disorders, this patient shows severe impairment in cognitive and motor function in the 10 months of follow up. He can only recognize some close persons and can not control the trunk and extremities well. The movement disorder which develops in the recovery phase and lasts for a long period may be associated with poor neurologic prognosis.
Key Words: Chorea, Pneumococcal meningitis


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