| Seroepidemiolgy of Cytomegalovirus in Taejon, Korea, in 1966 |
|
Kyung-Yil Lee |
|
Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea |
| 대전지역 소아에서의 Cytomegalovirus에 대한 혈청역학적 연구 |
|
이경일 |
|
가톨릭대학교 의과대학 소아과학교실 |
Correspondence:
Kyung-Yil Lee, Email: 1
|
|
|
|
|
| Abstract |
Purpose
: The prevalence of cytomegalovirus(CMV) depends mainly on socioeconomic status. It
is well noted that the prevalence of hepatitis A which is a representive agent of the fecal-oral
route has changed since the last 10-20 years. In order to evaluate the time of primary CMV
infection in childhood and to get help for interpretating the patterns of infection and prevention,
we studied the seroepidemiology of CMV in Taejon, Korea.
Methods
: We measured IgG anti-CMV antibody by microparticle enzyme immunoassay(CMV
IgG, Abbott) from 375 individuals from neonates(cord blood) to people over 30-years old.
Results
: The prevalence of anti-CMV IgG in neonate was 86.4%, 83.1% in 1-6 months, 84.4% in
7-12 months, 82.6% in 13-18 months, 84.2% in 19-24 months, 86.7% in 2-3 years, 80.0% in 4-6
years, 82.8% in 7-8 years, 80.0% in 10-12 years, 100% in 13-15 years, 100% in 16-19 years,
100% in 20-29 years and 100% over 30 years. In order to evaluate the critical time of CMV
infection with the consideration of transfered anti-CMV from mother, analyzed the prevalence of
anti-CMV IgG of 131 children aged from 1 month to 24 months with 2-month intervals, and
compared the results to that of anti-hepatitis A IgG. The positive rate of anti-CMV IgG is
significantly higher than that of anti-HAV IgG from 8 months of age.
Conclusion
: This study showed that most CMV infections in chidren in Taejon, Korea were
established within 12 months after birth. It also suggested that the perinatal infection plays an
important role in CMV infection. |
| Key Words:
Cytomegalovirus, Epidemiology, Anti-CMV IgG |
|
PDF Links
Download Citation
