| Pollen Allergy in Children(Ⅱ) : The Significance of Tree Pollen As a Causative Allergen in Children with Allergic Diseases |
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Soo-Young Lee, Jeong-Soe Park, Ki-Sun Lee, Chang Ho Hong |
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Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea |
| 소아의 화분 알레르기(II) : 호흡기 알레르기 질환을 지닌 소아에서 원인 항원으로서의 수목화분의 의의 |
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이수영, 박정서, 이기선, 홍창호 |
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아주대학교 의과대학 소아과학교실 |
Correspondence:
Soo-Young Lee, Email: 1
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| Abstract |
Purpose
: The positive rates of allergy skin test of pollens are relatively higher in children in
Suwon compared to other areas in Korea. To evaluate the significance of tree pollen as a
causative allergen, we undertook this study.
Methods
: In 252 children with asthma, scratch tests were done with 72 extracts, including 9 tree
pollen. Antigen specific serum IgE antibodies were measured by radioimmunoassay. In 2 children,
birch-bronchial challenges were performed.
Results
: By allergic skin tests, 231 of 252 children showed positive skin reactions to more than
1 antigen, and 102(44.2%) showed positive reactions to tree pollen extracts. Twenty-five(24.5%)
were house dust mites non-sensitive, tree pollen sensitive children. The skin test positivity to
individual antigens are as follows : D. pteronyssinus(72.7%), D. farinae(68.4%), hazel(53%), willow
(53%), birch(19.9%), oak(19.5%), beech(17.3%), alder(10.4%), ash(8.7%) and elm(7.4%). The degree
of skin reaction to tree pollen was relatively weaker than those of house dust mites. The positive
concordance rates between skin tests and specific IgE reactions to D. pteronyssinus, D. farinae
and tree pollens were 94.4%, 77.3% and 64.1%, respectively. Seven out of 25 mite non-sensitive
children had seasonal pollinosis and 2 children experienced early asthmatic responses due to
birch-bronchial challenge tests.
Conclusion
: Up to 44.2% of children with respiratory allergy showed positive reactions to tree
pollen extracts and 24.5% of them were house dust mites non-sensitive cases. Therefore, tree
pollen should be investigated as a causative allergen, regardless of a patient' s age. |
| Key Words:
Tree pollen, Causative allergen, Children, Asthma, Rhinitis |
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