| Clinical Effect and Complication of High Frequency Ventilation on Respiratory Failure |
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Man Hoe Hur, Yong Gook Kim, Ji Yun Baek, Sang Geel Lee |
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Department of Pediatrics, Taegu Fatima Hospital, Taegu, Korea |
| 신생아 호흡부전증에서 고빈도 호흡기 치료의 효과와 합병증에 관한 연구 |
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허만회, 김용국, 백지연, 이상길 |
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대구 파티마병원 소아과 |
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| Abstract |
Purpose
: Flow interruptor high frequency ventilator(HFV) on neonatal respiratory failure caused by various disorders has been applied in order to assess its therapeutic effect and safety.
Methods
: Premature babies below 1.8kg with respiratory failure from 1991 to 1997 in the Fatima neonatal intensive care unit(NICU) for 6 year and 4 months are included. Flow interruptor HFV with low intermittent mandatory ventilation(IMV) has been applied in 74 cases. If clinical symptom and arterial blood gas analysis(ABGA) became stable for 6-12 hrs, we started weaning aggressively.
Results
: Mean duration of HFV with low IMV was 5.4±4 days. Initial success rate of weaning was 63 cases(85.1%). Weaning failure rate was 11 cases(14.9%). Six cases was due to underlying sepsis. Four cases was caused by pneumothorax and one case resulted from patent ductus arteriosus(PDA) with congestive heart failure(CHF). Complication of HFV with combined low IMV was 5 cases of pneumothorax, 4 cases of grade Ⅲ intraventricular hemorrhage and one case of bronchopulmonary dysplasia(BPD). Eleven cases of stage Ⅲ or more retinopathy of prematurity(ROP) and 5 cases of periventricular leukomalasia(PVL) were confirmed.
Conclusion
: Flow interruptor HFV with low IMV can be used safely as conventional mechanical ventilators in the case of respiratory failure caused by various disorders. If MAP has been adjusted appropriately, incidence of pneumothorax and BPD are expected to diminish by aggressive weaning as clinical symptom become stable. |
| Key Words:
Flow interruptor high frequency ventilator, Neonatal respiratory failure |
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