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Clinical Observation of Parathion Intoxication in Infants and Children

Journal of the Korean Pediatric Society 1974;17(8):553-558.
Published online August 31, 1974.
Clinical Observation of Parathion Intoxication in Infants and Children
Seung Jung Lee, Kun Hee Park, Rhee Woo Kim, Chui Hong Peak, Ji Sub Oh, Dong Hak Shin
Department of Pediatrics, Presbyterian Hospital Daegu, Korea
소아 parathion 중독 56예에 관한 임상적 관찰
이 승 정, 박 건 희, 김 이 우, 백 철 홍, 오 지 섭, 신 동 학
대구동산기독병원 소아과
The following results have been obtained through the clinical observation of 56 cases of acute- parathion intoxication among the Pediatric in patients at Taegu Presbyterian Hospital during the past 13 years from 1961 to September 1973. 1. Sex incidence was higher in the boys than the girls and the majority (70%) of the patients was under 5 years old. 2. Accidents occurred more frequently during the summer and winter than other seasons, and there was no increase and decrease seen by years. 3. Parathion intoxication accidents took place more in the outskirt of city than the rural area. 4. Circumstance of intoxication was mainly caused by the careless parents who sprayed parathion. insecticide in the rooms. 5. The most frequent clinical symptoms were muscarinic action, miosis, salivation, sweating, stridor and unconscious states of C.N.S. action. 6. Case of Leukocytosis with left shifting was 52%, eosinopsnia was 66% and lymphopenia was 66%. 7. Serum cholinesterase was significantly decresed tlirough the method of Hesterin-Myasaki in all 9 cases to the minimum of 3. 2 mg/ml and maximum of 9. 5 mg/ml. 8. Combined treatment of atropine with 2-PAM chloride(pralidoxime chloride) revealed realtively better prognosis and faster recovery than using atropine alone.

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