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A Case of Allergic Bronchopulmonary Aspergillosis During Childhood

Journal of the Korean Pediatric Society 1999;42(2):284-288.
Published online February 15, 1999.
A Case of Allergic Bronchopulmonary Aspergillosis During Childhood
Kyoung Ah Ha1, Chang Keun Kim1, Churl Young Chung1, Jung Sook Kim2
1Department of Pediatrics, College of Medicine, Inje University, Seoul, Korea
2Department of Pediatrics, College of Medicine, Inje University, Seoul, Korea
소아 연령의 Allergic Bronchopulmonary Aspergillosis 1례
하경아1, 김창근1, 정철영1, 김정숙2
1인제대학교 의과대학 소아과학교실
2인제대학교 의과대학 방사선과학교실
Abstract
Allergic bronchopulmonary aspergillosis(ABPA) is an inflammatory disease which causes a hypersensitivity to Aspergillus spores growing in the bronchi. The clinical syndrome is characterized by asthma, recurrent pulmonary infiltrations or mucoid impaction, eosinophilia, and central bronchiectasis. A 12-year-old boy was admitted to our hospital because of right lower chest pain and cystic mass-like shadows on a chest X-ray film. He had asthma as an infant, but had no asthmatic symptoms on admission. Chest CT scan showed low density cystic mass of the right lower lobe. The total eosinophil count and IgE level were abnormally high. Test for immediate skin reaction to Aspergillus fumigatus was positive but precipitating antibody to Aspergillus antigen was negative. After steroid treatment, he became asymptomatic. Radiologic abnormalities including mass-like shadows were resolved by two months after the start of treatment and a follow-up high resolution CT scan obtained after clinical improvement revealed central saccular bronchiectasis. We report one case of ABPA with review of literature.
Key Words: Allergic bronchopulmonary aspergillosis, Asthma, Cystic mass, Central bronchiectasis


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