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Age-Related Criteria for Signal-Averaged Electrocardiographic Late Potentials in Children

Journal of the Korean Pediatric Society 1999;42(5):679-685.
Published online May 15, 1999.
Age-Related Criteria for Signal-Averaged Electrocardiographic Late Potentials in Children
Heon-Seok Han, Ki-Moon Cha
Department of Pediatrics, Chungbuk National University College of Medicine, Cheongju, Korea
소아에서 Signal-Averaged 심전도상 말기전압의 연령에 따른 기준치
한헌석, 차기문
충북대학교 의과대학 소아과학교실
Correspondence: 
Heon-Seok Han, Email: 1
Abstract
Purpose
: Ventricular late potentials have been shown to predict malignant ventricular arrhythmia and sudden cardiac death in patients with myocardial infarction and cardiomyopathy. Low amplitude and high frequency potentials at the end of the QRS complex can be detected on the body surface using signal-averaged electrocardiogram(SAECG). This study determines the age-related criteria of SAECG parameters and age-related differences.
Methods
: SAECGs were obtained in 58 healthy children in five age groups(<1mo, 1-11mo, 1- 5yr, 6-11yr, and 12-15yr). Three orthogonal leads(X, Y, Z) triggered with R-waves were amplified. In all recordings, a minimum of 250 beats were averaged after filtering with a 40Hz high- pass filter and 250Hz low-pass filter with noise level less than 0.7μV.
Results
: The filtered QRS(f-QRS) duration was low, and the root mean square amplitude of terminal 40ms of f-QRS(RMS40) was high before 6years of age. The duration of low amplitude signal under 40μV(LAS) and late duration(LD) changed little during childhood. The criteria for significant ventricular late potential were as follows : f-QRS>98ms, RMS40<105μV, LAS>27ms, and LD>40ms for <1mo; f-QRS>109ms, RMS40<98μV, LAS>20ms, and LD>49ms for 1-11mo; f-QRS>114ms, RMS40<33μV, LAS>33ms, and LD>39ms for 1-5yr; f-QRS>112ms, RMS40<39 μV, LAS>30ms, and LD>45ms for 6-11yr; f-QRS>117ms, RMS40<18μV, LAS>37ms, and LD>30ms for 12-15yr. RMS40 and LAS correlated with f-QRS duration(r=-0.75, and 0.45 respectively, P<0.05), suggesting that these parameters are associated with ventricular muscle thickness and ventricular conduction time.
Conclusion
: Age-related differences in SAECG parameters may be due to ventricular muscle thickness and ventricular conduction time. This should be considered for the evaluation of ventricular late potential.
Key Words: SAECG, Late potential, Age-related criteria, Childhood


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