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A Case of Transient Neonatal Pustular Melanosis

Journal of the Korean Pediatric Society 1999;42(6):879-882.
Published online June 15, 1999.
A Case of Transient Neonatal Pustular Melanosis
Young Ju Shin1, Ruey Tsai Wang1, Il Hwan Kim2, Kyung Burm Kim1, Young Kyoo Shin1, Baik Lin Eun1
1Departments of Pediatrics, College of Medicine, Korea University, Seoul, Korea
2Departments of Dermatology, College of Medicine, Korea University, Seoul, Korea
일과성 신생아 농포성 흑피증 1례
신영주1, 왕서재1, 김일환2, 김경범1, 신영규1, 은백린1
1고려대학교 의과대학 소아과학교실
2고려대학교 의과대학 피부과학교실
Baik Lin Eun, Email: 1
Transient neonatal pustular melanosis(TNPM) is a benign, self-limited, cutaneous disorder of unknown etiology. Significant physical findings are limited to the skin. Hematologic and serological tests are normal. Cultures of blood and pustule are negative. Biopsy specimens from pustules show a intracorneal or subcorneal separation containing neutrophils and also some eosinophils. TNPM produces only cutaneous lesions and requires no treatment. So it is essential to differentiate TNPM and other neonatal skin lesions. We experienced a case of TNPM in a male newborn with generalized superficial vesicopustules which developed into pigmented macules and report this case with review of related literatures.
Key Words: Transient neonatal pustular melanosis

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