Journal of the Korean Pediatric Society 1999;42(7):1019-1025.
Published online July 15, 1999.
A Childhood Case of Nephrotic Syndrome Complicated with Cerebral Venous Sinus Thrombosis Followed by Left Popliteal Artery Thrombosis
Si-Eun Lee1, Sue-Jin Lee1, Yang-Suk Jung1, Jae-Young Lim1, Chan-Hoo Park1, Hyang-Ok Woo1, Jin-Jong Yoo2, Hee-Shang Youn1
1Department of Pediatrics, Gyeongsang National University, College of Medicine, Chinju, Korea
2Department of Diagnostic Radiology, Gyeongsang National University, College of Medicine, Chinju, Korea
뇌정맥동 혈전증 후 슬와동맥 혈전증이 속발한 소아 신증후군 1례
이시은1, 이수진1, 정양숙1, 임재영1, 박찬후1, 우향옥1, 유진종2, 윤희상1
1경상대학교 의과대학 소아과학교실
2경상대학교 의과대학 진단방사선과학교실
Correspondence: 
Si-Eun Lee, Email: 1
Abstract
We report a 10-year-old male with steroid-responsive nephrotic syndrome which was complicated by cerebral venous sinus thrombosis including superior sagittal sinus and left popliteal artery thrombosis following 5 months later. At each thrombotic episode, he suffered from relapse of massive proteinuria with hypovolemic crisis, and from hemoconcentration with dehydration due to vomiting or diarrhea. Brain MR angiography confirmed thromboses of superior sagittal sinus, straight sinus, vein of Galen and occipital sinus. Diagnosis of left popliteal artery thrombosis was made according to the clinical observations including pulseless left dorsalis pedis artery, pain and coldness of left lower leg, and reperfusion injury of calf muscle after heparinization. Each thrombotic episode was successfully managed with heparinization, oral warfarin therapy and fresh frozen plasma for the antithrombin III replacement.
Key Words: Steroid responsive nephrotic syndrome, Cerebral venous sinus, Superior sagittal sinus, Popliteal artery, Thrombosis


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