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Three Cases of Subacute Necrotizing Lymphadenitis in Childhood

Journal of the Korean Pediatric Society 2000;43(3):423-427.
Published online March 15, 2000.
Three Cases of Subacute Necrotizing Lymphadenitis in Childhood
Min Hyang Park, Jin A Son, Jae Wook Go, Jae Yoon Kim, Don Hee Ahn
Department of Pediatrics, National Medical Center, Seoul, Korea
소아에서 발생한 아급성 괴사성 림프절염 3례
박민향, 손진아, 고재욱, 김재윤, 안돈희
국립의료원 소아과
Subacute necrotizing lymphadenitis was first reported by Kikuchi and Fujimoto in 1972. Young females no more than 30 years of age are mainly affected. It usually manifests as fever and cervical lymphadenopathy. We experienced three cases of subacute necrotizing lymphadenitis in an 11-year-old boy, a 12- year-old boy and an 11-year-old girl. Symptoms presented were URI signs, diarrhea, headache and weight loss along with fever and cervical lymphadenopathy. Fever persisted from 9 to 30 days and did not respond to antibiotics. We performed aspiration biopsy of cervical lymph node which was consistent with subacute necrotizing lymphadenitis in all cases. We used oral steroid in one case. Fever and lymphadenopathy subsided spontaneously within one month. There were no other complications.
Key Words: Subacute necrotizing lymphadenitis, Childhood

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