Warning: fopen(/home/virtual/pediatrics/journal/upload/ip_log/ip_log_2024-05.txt) [function.fopen]: failed to open stream: Permission denied in /home/virtual/pediatrics/journal/ip_info/view_data.php on line 82

Warning: fwrite(): supplied argument is not a valid stream resource in /home/virtual/pediatrics/journal/ip_info/view_data.php on line 83
A Case of Severe Hypertensive Pulmonary Edema Associated with Neuroblastoma during Chemotherapy

Journal of the Korean Pediatric Society 2000;43(4):573-577.
Published online April 15, 2000.
A Case of Severe Hypertensive Pulmonary Edema Associated with Neuroblastoma during Chemotherapy
Hee Suk Cho1, Hwang Min Kim1, Seok Won Park1, Jong Soo Kim1, Yoon Mi Kim2, Kwang Kil Lee2
1Department of Pediatrics, College of Medicine, Yonsei University Wonju, Wonju, Korea
2Department of Pediatrics and Pathology, College of Medicine, Yonsei University Wonju, Wonju, Korea
항암화학요법 도중 고혈압성 폐부종이 병발한 신경모세포종 1례
조희숙1, 김황민1, 박석원1, 김종수1, 김윤미2, 이광길2
1연세대학교 원주의과대학 소아과학교실
2연세대학교 원주의과대학 병리학교실
Abstract
The authors report a 7-year-old boy with neuroblastoma complicated by severe hypertension and pulmonary edema. Abdominal computed tomographic scan revealed a huge mass surrounding the aorta. After administration of cancer treatment, there was a marked increase in serum catecholamines level and hypertension, which resulted in pulmonary edema and heart failure. Alpha adrenergic blocking agents(prazocin, terazocin) were administrated, successfully controlling the hypertension. The tumor differentiated to ganglioneuroblastoma after chemotherapy. The catecholamine production of the residual neuroblastoma must have increased because the treatment induced differentiation. It is important to watch for the development of hypertension during the treatment of neuroblastoma.
Key Words: Neuroblastoma, Hypertension, Pulmonary edema, Catecholamine, Chemotherapy, Differentiation


METRICS Graph View
  • 2,465 View
  • 12 Download