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Clinical Evaluation of Cyclic Vomiting Syndrome

Journal of the Korean Pediatric Society 2000;43(9):1223-1231.
Published online September 15, 2000.
Clinical Evaluation of Cyclic Vomiting Syndrome
Jung Mee Cheon, Mee Ryung Um, Mun Hyang Lee, Nam Seon Beck
Department of Pediatrics, Sungkyunkwan University School of Medicine, Samsung Cheil Hospital, Seoul, Korea
주기성 구토증에 대한 임상적 고찰
천정미, 엄미령, 이문향, 백남선
성균관대학교 의과대학 삼성제일병원 소아과
: To obtain basic data on cyclic vomiting syndrome(CVS) and clinical findings of CVS.
: Fifteen patients diagnosed as CVS from April 1995 to July 1999 were enrolled in this study.
: Among 15 children with CVS(11 boys, 4 girls), 4 patients were put in the migraine group and 11 patients in non-migraine group. The onset age ranged from 7 months to 11.4 years(mean : 5.5 years). The prodromal symptoms of the migraine group were headache, flank pain and unpleasant feeling, and those of the non-migraine group were abdominal pain and dizziness. Vomiting began at characteristic times specific for each individual in 73% of patients; in the migraine group, 75% had symptoms on arising in the morning. In the non-migraine group, 36% were wakened during the night and 27% had symptoms on arising in the morning and 9% had episodes beginning at other characteristic times and the remaining 27% at no characteristic times. Durations of episodes were of fairly uniform length and mostly between 2 days and 10 days. In regards to precipitating factors, stress was the most frequently mentioned and other reported precipitants included infections, and sensitivity to food and hot or cold weather. Continuous vomiting causes ketosis, electrolyte imbalance, poor growth, peptic esophagitis and other complications, including learning problems and psychosocial dysfunction. Both groups had positive response to prokinetic agents.
: There was no clinical differences between the migraine group and non-migraine group. The response to therapy was poor, but the response to prokinetic agents was better than that to anti-migraine agents.
Key Words: Cyclic vomiting syndrome, Migraine

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