| Epidemiologic Characteristics of T Serotyping in Relation to the Outbreak of Erythromycin Resistant Streptococcus pyogenes |
|
Sung-Ho Cha2, Kyu Jam Hwang1, Young Hee Lee1 |
1Laboratory of Molecular Bacteriology, National Institute of Health, Seoul, Korea
2Department of Pediatrics, Kyung Hee College of Medicine, Seoul, Korea |
| Erythromycin 내성 A군 연쇄구균 출현과 관련된 세포벽 T 단백 항원성 검사의 역학적 중요성 |
|
차성호2, 황규잠1, 이영희1 |
1국립보건원 분자세균과
2경희대학교 의과대학 소아과학교실 |
Correspondence:
Sung-Ho Cha, Email: tcha0319@netsgo.com
|
|
|
|
|
| Abstract |
Purpose
: The identification of antigenic specificity of Streptococcus pyogenes using T serotyping is important to understand biologic characteristics of microorganisms. We would like to disover the association of the occurrence of predominant T type, with possible outbreak of erythromycin resistant Streptococcus pyogenes in this country, which has been documented since the late 1990s.
Methods
: Throat swab cultures were taken from a total of 1,294 normal school children(Subject A) in two different geographical areas. A total of 92 strains(Subject B) were obtained from the patients with group A streptococcal infections from Jan. 1998 to Dec. 1998. All strains were serotyped with T protein antisera.
Results
: The distribution of T12 in Uljin increased from 4.2%(1996) to 45.7%(1998). T4 increased from 6.3% to 20.0%. Thirty-eight out of 92 strains were resistant to erythromycin. Twenty-seven out of 41 strains(T12) were multidrug resistant to erythromycin, clindamycin, and tetracycline.
Conclusion
: We can see the sudden increase in T12 strains, one of the strains that are resistant to erythromycin in 1998, compared with previous years. T protein serotyping could be epidemiologically useful as a screening methods for detecting erythromycin resistant group A streptococci in hospitals where the routine antibiotic sensitivity test dose not examin for streptococci. |
| Key Words:
Streptococcus pyogenes, Erythromycin, T serotype, Antibiotic sensitivity test, Epidemiology |
|
PDF Links
Download Citation
