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A Case of Measles Encephalopathy with Thalamic Lesion on Magnetic Resonance Imaging

Journal of the Korean Pediatric Society 2001;44(8):936-941.
Published online August 15, 2001.
A Case of Measles Encephalopathy with Thalamic Lesion on Magnetic Resonance Imaging
Dae Hun Pee1, Dae Jin Song1, Young Kyoo Shin1, Jung Hwa Lee1, Kee Hyoung Lee1, Baik Lin Eun1, Sang Hoon Cha2
1Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea
2Department of Radiology, College of Medicine, Korea University, Seoul, Korea
자기 공명 영상에서 시상의 이상을 보인 홍역 뇌증 1례
피대훈1, 송대진1, 신영규1, 이정화1, 이기형1, 은백린1, 차상훈2
1고려대학교 의과대학 소아과학교실
2고려대학교 의과대학 진단방사선과
Correspondence: 
Baik Lin Eun, Email: bleun@chollian.net
Abstract
We experienced a case of measles encephalopathy with thalamic lesion on magnetic resonance imaging(MRI) in a 12 year old boy. Measles symptoms such as fever, erythematous maculopapular rashes on whole body and cough with sputum appeared 4 days before neurologic signs such as agitation and drowsy-to-confused mentality. He showed remarkable motor dysfunction without evidence of sensory loss. MRI showed bilateral symmetrical T2/FLAIR hyper-intensities in both thalami, posterior putamina and brainstem. It also showed inhomogenous Gadolinium(Gd) enhancement. In his electroencephalogram(EEG), there was nonspecific cortical dysfunction. After 20 days of supportive care, his motor dysfunction improved to near-normal and follow-up MRI revealed nearly normalized thalamic region. Over this period, no sensory loss was noted. We report this case with review of related literatures.
Key Words: Measles, Encephalopathy, Thalamic Lesion, Motor dysfunction


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