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Clinical Features of Subacute Necrotizing Lymphadenitis in Children

Journal of the Korean Pediatric Society 2002;45(8):994-999.
Published online August 15, 2002.
Clinical Features of Subacute Necrotizing Lymphadenitis in Children
Ji Young Hong1, Sun Hwan Bae1, Wan Sup Kim2
1Department of Pediatrics, School of Medicine, Eulji University, Seoul, Korea
2Department of Pathology, School of Medicine, Eulji University, Seoul, Korea
소아 아급성 괴사성 림프절염의 임상적 특징
홍지영1, 배선환1, 김완섭2
1을지의과대학 소아과학교실
2을지의과대학 조직병리학교실
Sun Hwan Bae, Email: bsh3209@eulji.or.kr
: There is a predilection for subacute necrotizing lymphadenitis(SNL) in young Asian women. Few pediatric cases have been reported. This study was performed to evaluate clinical features of children with SNL.
: We retrospectively analyzed clinical features of 23 cases of SNL under 15 years of age identified in Nowon Eulji Hospital from February 1995 to January 2002. Two cases were diagnosed by excisional biopsy and 21 cases by fine needle aspiration.
: The ages ranged from 14 months to 14 years(mean 8.1?.8 years). The male to female ratio was 1 : 1.6. Ten cases(10/23) were diagnosed in 2000. The onset was more frequent in spring. The common presenting symptoms were neck mass(22/23), pain(12/20) and fever(8/18). Fever subsided within two weeks in seven out of eight and lymphadenopathy resolved within five months in 14 out of 15. The mean WBC count was 7,664?,454/mm3. Elevated levels of ESR(10/ 12) and lactate dehydrogenase(5/6) and positive reaction for CRP(3/4) were frequent. Radiologically measured greatest diameter of the enlarged lymph nodes was less than 2 cm in 14 out of 15. One case occurred in a child with alopecia areata and one case with type 1 diabetes. Clinical outcomes were good in 23 cases.
: SNL should be considered in children with cervical lymphadenopathy regardless of fever or pain. SNL seems not rare in pediatric groups in Korea.
Key Words: Subacute necrotizing lymphadenitis, Children

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