| The Prevalent Rates of Abnormal Serum
Aminotransferase Levels and Total Cholesterol
Levels among Adolescents with Obesity |
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Hyun Oh Jang1, Chong Guk Lee2, Yun Ju Kang3 |
1Department of Pediatrics, Seoul Paik Hospital, College of Medicine, Inje University, Seoul, Korea
2Department of Pediatrics, Ilsan Paik Hospital, College of Medicine, Inje University, Koyang, Korea
3Seoul School Health Center, Seoul, Korea |
| 청소년기 비만아에서 이상 혈청 간효소치 및총콜레스테롤치의 유병율 |
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장현오1, 이종국2, 강윤주3 |
1인제대학교 의과대학 서울백병원 소아과
2인제대학교 의과대학 일산백병원 소아과
3서울시학교보건원 |
Correspondence:
Chong Guk Lee, Email: chonglee@ilsanpaik.ac.kr
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| Abstract |
Purpose
: The purpose of this study was to look at prevalences of abnormal serum aminotransferase levels and abnormal serum total cholesterol levels among adolescents with obesity in Seoul area.
Methods
: Body mass index[BMI(kg/m2)], serum aspartate aminotransferase(AST) alanine aminotransferase(ALT), and total cholesterol levels were measured in 26,876 adolescents(male : 13,287, female : 13,589) of first grade of high school in Seoul between the ages of 15 and 16 years, enrolled in a large health examination survey by Seoul School Health Center(SSHC) in 2001. Obesity was defined as BMI more than 95th percentile for age and sex and normal weight was defined as BMI between 25th percentile and 75th percentile for age and sex. Abnormal levels of AST, ALT and total cholesterol were defined as more than 95th percentile for age and sex.
Results
: The BMI at 95th percentile was 28.7 in males and 26.9 in females. The prevalence of abnormal AST levels was higher in obesity group than in normal weight group. In males, those were 23.7% and 3.7%, respectively(P<0.01, χ2-value : 529.2). In females, those were 11.8% and 4.9 %, respectively(P<0.01, χ2-value : 56.3). The prevalence of abnormal ALT levels was significantly higher in the obesity group compared with the normal weight group. In males, those were 33.9% and 1.7%, respectively(P<0.01, χ2-value : 1,693.4). In females, those were 22.3% and 3.9%, repectively(P<0.01, χ2-value : 397.6). The prevalence of abnormal total cholesterol levels was higher in the obesity group than in the normal weight group. In males, those were 16.8% and 3.5%, respectively(P<0.01, χ2-value : 268.3). In females, those were 9.0% and 5.4%, respectively(P<0.01, χ2- value : 14.2).
Conclusion
: This study revealed that the prevalences of abnormal AST, ALT and total cholesterol level were higher in the obese group than in the normal weight group. |
| Key Words:
Obesity, BMI, AST, ALT, Total cholesterol |
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