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A Comparison of Clinical Manifestations in Neonates and Infants Infected by Respiratory Syncytial Virus

Korean Journal of Pediatrics 2004;47(9):949-952.
Published online September 15, 2004.
A Comparison of Clinical Manifestations in Neonates and Infants Infected by Respiratory Syncytial Virus
In Suk Lim1, Min Joo Shim1, Byung Eui Kim1, Ju Young Chung1, Chang Keun Kim1, Myoung Jae Chey1, Sang Woo Kim1, Soung Hee Kim2, Tae Hee Han3
1Departments of Pediatrics, College of Medicine, Inje University, Seoul, Korea
2Departments of Diagnostic Radiology, College of Medicine, Inje University, Seoul, Korea
3Departments of Pediatrics, Laboratory Medicine, College of Medicine, Inje University, Seoul, Korea
Respiratory Syncytial Virus에 감염된 신생아와 영아에서 임상 양상에 관한 연구
임인숙1, 심민주1, 김병의1, 정주영1, 김창근1, 최명재1, 김상우1, 김성희2, 한태희3
1인제대학교 의과대학 상계백병원 소아과
2인제대학교 의과대학 상계백병원 진단방사선과
3인제대학교 의과대학 상계백병원 진단검사의학과
Correspondence: 
Byung Eui Kim, Email: kbetel@sanggyepaik.ac.kr
Abstract
Purpose
: This study was performed to evaluate of clinical manifestations of neonatal respiratory syncytial virus(RSV) infection, and to evaluate of differences of clinical manifestations between the neonates and infants who were infected by RSV.
Methods
: We reviewed the medical record of 75 children who were younger than 12 months of age and infected by RSV. We classified then into a neonatal group(n=30) and an infantile group(n=45) and compared the neonatal group with the infantile group by clinical manifestation and chest X-ray.
Results
: Fever was more significant in the infantile group than the neonatal group(P=0.0256). The chest wall retraction was seen significantly in the neonatal group(P=0.0034). The study didn't show a significant difference in wheezing or rale between the two groups. There was not any significant difference in cyanosis and apnea between the two groups but the symptoms appeared more frequently in the neonatal group. With regard to chest X-rays, pneumonia is seen more frequently in the neonatal group(23/30, 76.67%) and bronchiolitis is seen more frequently in the infantile group (25/45, 55.55%).
Conclusion
: Neonatal RSV infections appear with fever less than infantile RSV infection and may appear with mild clinical manifestations, but chest retraction and pneumonia are more frequently present than in the infantile group. Therefores, neonate needs careful observation and treatment.
Key Words: Respiratory syncytial virus, Neonate, Infant


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