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A Case of Childhood Acute Lymphoblastic Leukemia with Monosomy 20 and Parotid Gland Involvement

Korean Journal of Pediatrics 2004;47(12):1347-1350.
Published online December 15, 2004.
A Case of Childhood Acute Lymphoblastic Leukemia with Monosomy 20 and Parotid Gland Involvement
Hae Rim Kim1, Seung Ah Hong1, Byung Kyu Choe1, Heung Sik Kim1, Jung Sook Ha2, Dong Seok Jeon2, Yu Na Kang3
1Department of Pediatrics, Keimyung University, School of Medicine, Daegu, Korea
2Department of Laboratory Medicine, Keimyung University, School of Medicine, Daegu, Korea
3Department of Pathology, Keimyung University, School of Medicine, Daegu, Korea
이하선 침범과 단일염색체(Monosomy) 20이 동반된 소아 급성 림프구성 백혈병 1례
김혜림1, 홍승아1, 최병규1, 김흥식1, 하정숙2, 정동석2, 강유나3
1계명대학교 의과대학 소아과학교실
2계명대학교 의과대학 진단검사의학교실
3계명대학교 의과대학 병리학교실
Correspondence: 
Heung Sik Kim, Email: kimhs@dsmc.or.kr
Abstract
Hypodiploidy exists in 3-15% of patients with childhood acute lymphoblastic leukemia(ALL) and is associated with a poor prognosis. Monosomy 7 and monosomy 20 account for most karyotypic abnormalities in patients in whom whole chromosomes are lost and their incidences are rare. Parotid tumors in the pediatric age group are unusual and in 1996, there was a case of invasion of the parotid glands of ALL in a 6-year-old boy with swelling of both parotid glands. But invasion of acute lymphocytic leukemia to the parotid gland has not yet been reported in Korea. Here, we report a 33 month-old boy with swelling of both parotid glands who was diagnosed to have ALL with monosomy 20 & parotid gland invasion.
Key Words: ALL, Monosomy 20, Parotid gland


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