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A Case of Idiopathic Interstitial Pneumonia in Childhood

Korean Journal of Pediatrics 2005;48(3):327-332.
Published online March 15, 2005.
A Case of Idiopathic Interstitial Pneumonia in Childhood
Su-Jin Lee1, Eon-Woo Shin1, Eun-Young Park1, Phil-Soo Oh1, Kon-Hee Lee1, Kwang-Nam Kim1, Ho-Seung Shin2, Il-Seung Lee3
1Department of Pediatrics, College of Medicine, Hallym University, Seoul, Korea
2Department of Thoracic and Cardiovascular Surgery, College of Medicine, Hallym University, Seoul, Korea
3Department of Radiology, College of Medicine, Hallym University, Seoul, Korea
소아 특발성 간질성 폐렴 1례
이수진1, 신언우1, 박은영1, 오필수1, 이건희1, 김광남1, 신호승2, 이일성3
1한림대학교 의과대학 소아과학교실
2한림대학교 의과대학 흉부외과학교실
3한림대학교 의과대학 영상의학과학교실
Kon-Hee Lee, Email: lkhchj@shinbiro.com
Interstitial lung disease refers to a group of pulmonary disorders characterized by inflammation of the interstitium, derangements and loss of alveolar capillary units leading to disruption of alveolar gas exchange, which induces symptoms of restrictive lung disease. Cases of interstitial pneumonia in children are uncommon and mostly have unknown causes. We have experienced an 8-year old boy who had symptoms of cyanosis, dry cough, dyspnea and abrupt weight loss. He had not been exposed to organic dusts, allergens or any other systemic disease infections. Chest radiology showed diffuse ground glass opacity in both lung fields. High resolution computed tomography(HRCT) showed multiple small patchy areas of consolidation with an underlying ground glass appearance in both lungs. The pathologic findings of lung biopsy tissue showed patchy areas of interstitial fibrosis, alveolar obliteration and nodular fibrotic areas, strongly suggesting interstitial pneumonia. No specific finding of viral inclusion or any other evidence of infection was found under electromicroscopy. We used peak flow meters to compare functional improvement. Forced expiratory volume in one second (FEV1) was decreased to 25 percent of predicted value. The boy was given treatment with prednisone and showed improvements in HRCT findings after two months. He was able to tolerate easy exercise in school and showed clinical improvements after one year of follow up.
Key Words: Interstitial pneumonia , Childhood

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